Analytical Data
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基因名
ZNF238
- Application
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别名
C2H2171; 58 kDa repressor Protein; C2H2 171; RP58; TAZ 1; TAZ-1; TAZ1; Transcriptional repressor RP58; Translin associated zinc finger Protein 1; Translin-associated zinc finger Protein 1; ZBTB18; Zinc finger and BTB domain containing Protein 18; Zinc finger and BTB domain-containing Protein 18; Zinc finger Protein 238; Zinc finger Protein C2H2 171; Zinc finger Protein C2H2-171; ZN238_HUMAN; ZNF238
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q99592
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表达区间
1-522 aa
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氨基酸序列
MEFPDHSRHL LQCLSEQRHQ GFLCDCTVLV GDAQFRAHRA VLASCSMYFH LFYKDQLDKR DIVHLNSDIV TAPAFALLLE FMYEGKLQFK DLPIEDVLAA ASYLHMYDIV KVCKKKLKEK ATTEADSTKK EEDASSCSDK VESLSDGSSH IAGDLPSDED EGEDEKLNIL PSKRDLAAEP GNMWMRLPSD SAGIPQAGGE AEPHATAAGK TVASPCSSTE SLSQRSVTSV RDSADVDCVL DLSVKSSLSG VENLNSSYFS SQDVLRSNLV QVKVEKEASC DESDVGTNDY DMEHSTVKES VSTNNRVQYE PAHLAPLRED SVLRELDRED KASDDEMMTP ESERVQVEGG MESSLLPYVS NILSPAGQIF MCPLCNKVFP SPHILQIHLS THFREQDGIR SKPAADVNVP TCSLCGKTFS CMYTLKRHER THSGEKPYTC TQCGKSFQYS HNLSRHAVVH TREKPHACKW CERRFTQSGD LYRHIRKFHC ELVNSLSVKS EALSLPTVRD WTLEDSSQEL WK
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分子量
58.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZNF238, also known as Zinc Finger Protein 238, is a member of the Krüppel-like zinc finger protein family, which plays crucial roles in various biological processes, including transcription regulation, cell differentiation, and development. Recent studies have highlighted its potential involvement in cancer progression and neurological disorders, suggesting that ZNF238 acts as a tumor suppressor and is implicated in maintaining neuronal health. The interest in ZNF238 recombinant protein arises from the need to understand its complex interactions and functional mechanisms at a molecular level. By producing ZNF238 as a recombinant protein, researchers aim to investigate its binding affinities, post-translational modifications, and interactions with other proteins or DNA sequences. The insights gained from such studies could elucidate the pathways influenced by ZNF238, providing valuable information for therapeutic targeting in diseases where ZNF238 is dysregulated. Furthermore, the availability of purified ZNF238 protein allows for the development of assays that can screen for small molecules or compounds that might modulate its activity, paving the way for novel treatments in oncology and neurology. Thus, the study of ZNF238 recombinant protein not only enhances our understanding of its biological functions but also holds promise for biotechnological and pharmaceutical applications.
