Analytical Data
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Gene name
ZNF192
- Application
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Alternative Names
ZKSCAN8; ZNF192; Zinc finger Protein with KRAB and SCAN domains 8; LD5-1; Zinc finger Protein 192
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q15776
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Expression Region
1-578 aa
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AA Sequence
MAEESRKPSAPSPPDQTPEEDLVIVKVEEDHGWDQESSLHESNPLGQEVFRLRFRQLRYQ ETLGPREALIQLRALCHQWLRPDLNTKEQILELLVLEQFLTILPEELQTLVKEHQLENGE EVVTLLEDLERQIDILGRPVSARVHGHRVLWEEVVHSASAPEPPNTQLQSEATQHKSPVP QESQERAMSTSQSPTRSQKGSSGDQEMTATLLTAGFQTLEKIEDMAVSLIREEWLLDPSQ KDLCRDNRPENFRNMFSLGGETRSENRELASKQVISTGIQPHGETAAKCNGDVIRGLEHE EARDLLGRLERQRGNPTQERRHKCDECGKSFAQSSGLVRHWRIHTGEKPYQCNVCGKAFS YRSALLSHQDIHNKVKRYHCKECGKAFSQNTGLILHQRIHTGEKPYQCNQCGKAFSQSAG LILHQRIHSGERPYECNECGKAFSHSSHLIGHQRIHTGEKPYECDECGKTFRRSSHLIGH QRSHTGEKPYKCNECGRAFSQKSGLIEHQRIHTGERPYKCKECGKAFNGNTGLIQHLRIH TGEKPYQCNECGKAFIQRSSLIRHQRIHSGEKSESISV
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Molecular Weight
65.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF192, a member of the zinc finger protein family, plays a crucial role in various biological processes, including transcriptional regulation, cell differentiation, and response to stress signals. Its functional importance has sparked significant interest in understanding the molecular mechanisms underlying its activity. Recent studies have suggested that ZNF192 may act as a transcriptional repressor, influencing the expression of target genes involved in cell proliferation and apoptosis. Furthermore, aberrant expression of ZNF192 has been associated with several diseases, including cancer, where it could contribute to tumorigenesis through the dysregulation of key cellular pathways. The recombinant production of ZNF192 protein is essential for elucidating its structure and function, as well as for exploring potential therapeutic strategies that target its activity in various diseases. Understanding the specific interactions and mechanisms by which ZNF192 operates can pave the way for novel approaches in drug development and disease management. As research continues to uncover the complexities of ZNF192's role in cellular processes, the recombinant protein will serve as a valuable tool in both basic and applied biomedical research.
