Analytical Data
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Gene name
ZNF181
- Application
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Alternative Names
ZNF181; Zinc finger Protein 181; HHZ181
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q2M3W8
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Expression Region
1-571 aa
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AA Sequence
MPQVTFNDVA IDFTHEEWGW LSSAQRDLYK DVMVQNYENL VSVAGLSVTK PYVITLLEDG KEPWMMEKKL SKGMIPDWES RWENKELSTK KDNYDEDSPQ TVIIEKVVKQ SYEFSNSKKN LEYIEKLEGK HGSQVDHFRP AILTSRESPT ADSVYKYNIF RSTFHSKSTL SEPQKISAEG NSHKYDILKK NLPKKSVIKN EKVNGGKKLL NSNKSGAAFS QGKSLTLPQT CNREKIYTCS ECGKAFGKQS ILNRHWRIHT GEKPYECREC GKTFSHGSSL TRHLISHSGE KPYKCIECGK AFSHVSSLTN HQSTHTGEKP YECMNCGKSF SRVSHLIEHL RIHTQEKLYE CRICGKAFIH RSSLIHHQKI HTGEKPYECR ECGKAFCCSS HLTRHQRIHT MEKQYECNKC LKVFSSLSFL VQHQSIHTEE KPFECQKCRK SFNQLESLNM HLRNHIRLKP YECSICGKAF SHRSSLLQHH RIHTGEKPYE CIKCGKTFSC SSNLTVHQRI HTGEKPYKCN ECGKAFSKGS NLTAHQRVHN GEKPNSVVSV EKPLDYMNHY TCEKSYRRET V
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Molecular Weight
65.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF181, a member of the zinc finger transcription factor family, has garnered attention in recent research due to its potential roles in gene regulation and its implications in various biological processes, including cell differentiation, development, and cancer. This protein contains multiple zinc finger motifs, which are known for their ability to bind DNA and influence transcriptional activity. The study of ZNF181 has been motivated by its suggested involvement in the regulation of specific gene expression, which may impact tumorigenesis and cellular responses to stress. Recent advancements in molecular biology techniques have enabled the generation of recombinant ZNF181 proteins, facilitating detailed investigations into their structure and function. Understanding the functional domains and interaction partners of ZNF181 could unveil insights into its biological significance and potential as a therapeutic target. Furthermore, the characterization of ZNF181 through recombinant protein studies can aid in elucidating its role in various signaling pathways and its contribution to disease mechanisms, particularly in cancers where dysregulation of transcription factors is prevalent. Thus, the research on ZNF181 not only enhances our knowledge of zinc finger proteins but also opens avenues for potential clinical applications in cancer treatment and regenerative medicine.
