Analytical Data
-
基因名
ZNF143
- Application
-
别名
ZNF143; SBF; STAF; Zinc finger Protein 143; SPH-binding factor; Selenocysteine tRNA gene transcription-activating factor; hStaf
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P52747
-
表达区间
1-638 aa
-
氨基酸序列
MLLAQINRDS QGMTEFPGGG MEAQHVTLCL TEAVTVADGD NLENMEGVSL QAVTLADGST AYIQHNSKDA KLIDGQVIQL EDGSAAYVQH VPIPKSTGDS LRLEDGQAVQ LEDGTTAFIH HTSKDSYDQS ALQAVQLEDG TTAYIHHAVQ VPQSDTILAI QADGTVAGLH TGDATIDPDT ISALEQYAAK VSIDGSESVA GTGMIGENEQ EKKMQIVLQG HATRVTAKSQ QSGEKAFRCE YDGCGKLYTT AHHLKVHERS HTGDRPYQCE HAGCGKAFAT GYGLKSHVRT HTGEKPYRCS EDNCTKSFKT SGDLQKHIRT HTGERPFKCP FEGCGRSFTT SNIRKVHVRT HTGERPYYCT EPGCGRAFAS ATNYKNHVRI HTGEKPYVCT VPGCDKRFTE YSSLYKHHVV HTHSKPYNCN HCGKTYKQIS TLAMHKRTAH NDTEPIEEEQ EAFFEPPPGQ GEDVLKGSQI TYVTGVEGDD VVSTQVATVT QSGLSQQVTL ISQDGTQHVN ISQADMQAIG NTITMVTQDG TPITVPAHDA VISSAGTHSV AMVTAEGTEG EQVAIVAQDL AAFHTASSEM GHQQHSHHLV TTETRPLTLV ATSNGTQIAV QLGEQPSLEE AIRIASRIQQ GETPGLDD
-
分子量
68.8 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF143, a member of the zinc finger protein family, is known for its role in transcription regulation and DNA-binding activities, making it a significant player in various biological processes. Research on ZNF143 has gained momentum due to its involvement in critical cellular functions, including gene expression, cellular differentiation, and the response to environmental stimuli. Its interactions with DNA sequences, particularly within promoter regions, are crucial for understanding gene regulation mechanisms. Moreover, ZNF143 has been implicated in various diseases, including cancer, where its dysregulation can contribute to oncogenesis. The generation of recombinant ZNF143 protein has become essential for elucidating its structural and functional properties. By producing this protein in vitro, researchers can study its DNA-binding characteristics, identify target genes, and investigate its influence on transcriptional networks. Understanding the precise biochemical interactions mediated by ZNF143 could provide insights into its role in health and disease, paving the way for potential therapeutic strategies targeting its pathways. This research contributes to a deeper comprehension of the intricacies of gene regulation and highlights the importance of ZNF143 in cellular biology.
