Cat: PAX2000-12714

Recombinant Human ZKSCAN3 Protein,GST

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Analytical Data

  • Gene name

    ZKSCAN3

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    dJ874C20.1; mszf35; SCAN-KRAB-zinc finger Protein; Skz1; Zf47; Zfp-47; ZFP306; Zfp307; Zfp47; Zinc finger and SCAN domain containing Protein 13; Zinc finger and SCAN domain-containing Protein 13; Zinc finger Protein 306; Zinc finger Protein 306; isoform CRA_a; Zinc finger Protein 307; Zinc finger Protein 309; Zinc finger Protein 47 homolog; Zinc finger Protein with KRAB and SCAN domains 3; Zinc finger Protein with KRAB and SCAN domains 3; Zinc finger Protein zfp47; Zinc finger with KRAB and SCAN domains 3; ZKSC3_HUMAN; ZKSCAN3; ZNF309; ZSCAN13; ZSCAN35

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9BRR0

  • Expression Region

    1-538 aa

  • AA Sequence

    MARELSESTALDAQSTEDQMELLVIKVEEEEAGFPSSPDLGSEGSRERFRGFRYPEAAGPREALSRLRELCRQWLQPEMHSKEQILELLVLEQFLTILPGNLQSWVREQHPESGEEVVVLLEYLERQLDEPAPQVSGVDQGQELLCCKMALLTPAPGSQSSQFQLMKALLKHESVGSQPLQDRVLQVPMLAHGGCCREDAVVASRLTPESQGLLKVEDVALTLTPEWTQQDSSQGNLCRDEKQENHGSLVSLGDEKQTKSRDLPPAEELPEKEHGKISCHLREDIAQIPTCAEAGEQEGRLQRKQKNATGGRRHICHECGKSFAQSSGLSKHRRIHTGEKPYECEECGKAFIGSSALVIHQRVHTGEKPYECEECGKAFSHSSDLIKHQRTHTGEKPYECDDCGKTFSQSCSLLEHHRIHTGEKPYQCSMCGKAFRRSSHLLRHQRIHTGDKNVQEPEQGEAWKSRMESQLENVETPMSYKCNECERSFTQNTGLIEHQKIHTGEKPYQCNACGKGFTRISYLVQHQRSHVGKNILSQ

  • Molecular Weight

    87 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ZKSCAN3, a member of the zinc finger protein family, has garnered attention in recent years due to its implicated roles in various cellular processes and its potential implications in human diseases. Primarily recognized for its involvement in transcriptional regulation, ZKSCAN3 has been shown to influence gene expression patterns associated with cell proliferation, differentiation, and apoptosis. Studies have indicated that dysregulation of ZKSCAN3 may play a pivotal role in oncogenesis, particularly in certain types of cancer, highlighting its potential as a biomarker or therapeutic target. Research efforts have focused on understanding the mechanisms through which ZKSCAN3 exerts its effects, including its interactions with other proteins and DNA, as well as its response to cellular stressors. Additionally, the recombinant expression of ZKSCAN3 has facilitated investigations into its functional properties, allowing for the exploration of its biological significance in a variety of contexts. As a result, ZKSCAN3 represents a promising avenue for biomedical research, with the potential to contribute to improved strategies for cancer diagnosis and treatment.

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