Analytical Data
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Gene name
ZFYVE28
- Application
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Alternative Names
ZFYVE28; KIAA1643; LST2Lateral signaling target Protein 2 homolog; hLst2; Zinc finger FYVE domain-containing Protein 28
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9HCC9
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Expression Region
1-887 aa
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AA Sequence
MMNRFRKWLYKPKRSDPQLLARFYYADEELNQVAAELDSLDGRKDPQRCTLLVSQFRSCQDNVLNIINQIMDECIPQDRAPRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNRELESMAMRPLAKELTRSLEDVRGALRDQALRDLNTYTEKMREALRHFDVLFAEFELSYVSAMVPVKSPREYYVQQEVIVLFCETVERALDFGYLTQDMIDDYEPALMFSIPRLAIVCGLVVYADGPLNLDRKVEDMSELFRPFHTLLRKIRDLLQTLTEEELHTLERNLCISQDVEFPIRADVQGPAALAPALSAPLPPEGPLSAKAKDPDAELACSMQYDDQELEQLSRMVHRAGDEMSSLLSPPIACQSPAHRPGAEGSPGGEASPGRPRLRSGSDEEERVFFMDDVEGTAEALARPESPAGPFGWAGSTWADPQEKGQGGPGGAAGISLPASEKEEDLSNNNLEAEGTDGASLAGTSSCSCLDSRLHLDGWEVGADDAETAEMIAHRTGGMKLSATVIFNPKSPTSLDSAVATQEAASEPVAEGMDGGPHKLSTGATNCLLHSCVCCGSCGDSREDVVERLREKCSPGGVIGASYAAGLAKASDRAPERQEEAPPPSEDASNGREPKAPTSDKCLPHTSGSQVDTASGLQGEAGVAGQQEPEARELHAGSPPAHEAPQALSGSSSSTAGSCSSDKMGPEAAPAATHAAPQATREKIRSRFHGSHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFEVMATKPETDDKEKLRKVTQTLRSAALEDCALCQETLSSSELAAKTRDGDFEDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCYMFHVTPFYSDKAGL
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Molecular Weight
122.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZFYVE28 is a member of the ZFYVE (zinc finger FYVE domain) protein family, known for its role in cellular processes such as membrane trafficking, endocytosis, and signal transduction. Recent studies have highlighted its potential involvement in various biological pathways, including those related to cancer progression and immune response. It contains a FYVE domain, which is crucial for binding to phosphatidylinositol 3-phosphate (PI3P), a lipid that plays a significant role in cellular signaling and membrane dynamics. Understanding the functional mechanisms of ZFYVE28 could provide insights into its contributions to cell physiology and pathology. The investigation of ZFYVE28 recombinant protein is particularly essential for elucidating its role in these processes, as it allows for the analysis of the protein's structure-function relationship and its interactions with other cellular components. Researchers are increasingly focusing on ZFYVE28 to explore its potential as a biomarker or therapeutic target in diseases where its expression or function is altered, including various cancers and metabolic disorders. Furthermore, the production and characterization of the ZFYVE28 recombinant protein enable the development of specific antibodies and inhibitors, which could aid in both basic research and clinical applications. Overall, the study of ZFYVE28 and its recombinant forms represents a promising area of research that may unlock new avenues for therapeutic interventions and enhance our understanding of cellular mechanisms underpinning health and disease.
