Analytical Data
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基因名
ZFP42
- Application
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别名
hREX-1; Reduced Expression 1 Protein; Reduced expression Protein 1; Rex-1; REX1; REX1 transcription factor; Zfp-42; Zfp42; ZFP42 zinc finger Protein; ZFP42_HUMAN; Zinc finger Protein 42 homolog; Zinc finger Protein 754; ZNF754
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96MM3
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表达区间
1-310 aa
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氨基酸序列
MSQQLKKRAKTRHQKGLGGRAPSGAKPRQGKSSQDLQAEIEPVSAVWALCDGYVCYEPGPQALGGDDFSDCYIECVIRGEFSQPILEEDSLFESLEYLKKGSEQQLSQKVFEASSLECSLEYMKKGVKKELPQKIVGENSLEYSEYMTGKKLPPGGIPGIDLSDPKQLAEFARKKPPINKEYDSLSAIACPQSGCTRKLRNRAALRKHLLIHGPRDHVCAECGKAFVESSKLKRHFLVHTGEKPFRCTFEGCGKRFSLDFNLRTHVRIHTGEKRFVCPFQGCNRRFIQSNNLKAHILTHANTNKNEQEGK
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分子量
61.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZFP42, also known as Rex1, is a zinc finger protein that plays a crucial role in stem cell biology and early embryonic development. It is primarily expressed in embryonic stem cells (ESCs) and is involved in maintaining pluripotency, the ability of a stem cell to differentiate into various cell types. Research has shown that ZFP42 is essential for the self-renewal of ESCs and influences their fate decisions during the differentiation process. Its expression is tightly regulated, and aberrations can lead to impaired stem cell function or contribute to developmental disorders. Recent studies have focused on the mechanisms by which ZFP42 interacts with other transcription factors and chromatin regulators to modulate gene expression. The recombinant production of ZFP42 protein allows for detailed functional assays to elucidate its role in stem cell maintenance and differentiation pathways. Furthermore, understanding the specific interactions and regulatory networks involving ZFP42 may provide insights into regenerative medicine and therapeutic strategies for tissue engineering and stem cell therapy. Research on ZFP42 has significant implications for enhancing the efficiency of stem cell-based therapies and for developing novel approaches to manipulate stem cell behavior in regenerative medicine. As such, ZFP42 represents a key target for further investigation in the field of developmental biology and stem cell research.
