Analytical Data
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基因名
THEX1
- Application
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别名
3'-5' exoribonuclease 1. EC:3.1.13.1. 3'-5' exonuclease ERI1. Eri-1 homolog. Histone mRNA 3'-end-specific exoribonuclease. Histone mRNA 3'-exonuclease 1. Protein 3'hExo. HEXO
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IV48
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表达区间
1-349 aa
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氨基酸序列
MEDPQSKEPAGEAVALALLESPRPEGGEEPPRPSPEETQQCKFDGQETKGSKFITSSASDFSDPVYKEIAITNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKLMLKESNFADSYYDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDWMKLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPHCGLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFRK
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分子量
66.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
THEX1 is a recombinant protein that has garnered significant interest in the field of molecular biology due to its role in various cellular processes. It was initially identified as a key player in the regulation of gene expression and has been linked to several important biological functions, including cell differentiation, proliferation, and apoptosis. Research on THEX1 has revealed its involvement in signaling pathways that are critical for maintaining cellular homeostasis and responding to external stimuli. The protein's unique structural features, such as its conserved domains and potential post-translational modifications, make it a target of interest for studies aimed at deciphering the molecular mechanisms underlying its functions. Furthermore, THEX1 has been implicated in various diseases, including certain forms of cancer, where its expression levels and activity can significantly impact tumor progression and response to therapy. Thus, understanding THEX1’s biological role and mechanisms of action not only provides insights into fundamental cellular processes but also opens avenues for potential therapeutic interventions. The use of recombinant technology to produce THEX1 in sufficient quantities has facilitated detailed functional studies, allowing researchers to explore its properties in vitro and in vivo. As such, ongoing research aims to elucidate the precise roles of THEX1 in health and disease, contributing to the broader understanding of protein functions in cellular contexts and their implications in treating diseases associated with dysregulated protein activity.
