Analytical Data
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基因名
TGIF2
- Application
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别名
5' TG 3' interacting factor 2; 5''-TG-3''-interacting factor 2; Homeobox Protein TGIF2; TGF (beta) induced transcription factor 2; TGF beta induced factor 2; TGF-beta-induced transcription factor 2; TGFB induced factor 2; TGFB-induced factor 2; Tgif2; TGIF2_HUMAN; Transforming growth factor beta induced factor 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9GZN2
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表达区间
2-237 aa
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氨基酸序列
SDSDLGEDE GLLSLAGKRK RRGNLPKESV KILRDWLYLH RYNAYPSEQE KLSLSGQTNL SVLQICNWFI NARRRLLPDM LRKDGKDPNQ FTISRRGGKA SDVALPRGSS PSVLAVSVPA PTNVLSLSVC SMPLHSGQGE KPAAPFPRGE LESPKPLVTP GSTLTLLTRA EAGSPTGGLF NTPPPTPPEQ DKEDFSSFQL LVEVALQRAA EMELQKQQDP SLPLLHTPIP LVSENPQ
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分子量
25.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TGIF2, or TG-interacting factor 2, is a member of the TGIF family of proteins that serves as a crucial transcriptional repressor involved in embryonic development and signaling pathways. Abnormal regulation of TGIF2 has been associated with various diseases, including cancers, making it a significant focus for research. Studies have shown that TGIF2 interacts with several key signaling cascades, particularly the TGF-β and Wnt pathways, which are vital for cellular processes such as differentiation, proliferation, and apoptosis. The understanding of TGIF2's function and its interactions has implications for developmental biology and therapeutic strategies for diseases linked to its dysregulation. Moreover, TGIF2's unique structural features and its ability to bind DNA and other proteins make it an interesting target for the development of recombinant proteins that can be used to study its mechanisms of action in vitro and in vivo. Ongoing research in this area aims to elucidate the precise role of TGIF2 in cellular contexts and its potential as a biomarker or therapeutic target, thereby contributing to the understanding of tumorigenesis and developmental disorders.
