Cat: PA1000-8166

Recombinant Human SCT Protein,His

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Analytical Data

  • Gene name

    SCT

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    SCT;Secretin

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P09683

  • Expression Region

    28-54aa

  • AA Sequence

    HSD GTFTSELSRL REGARLQRLL QGLV

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

SCT (Suprachiasmatic nucleus Circadian Timing) recombinant proteins have garnered increasing attention in the field of circadian biology due to their crucial role in regulating circadian rhythms in mammals. The suprachiasmatic nucleus (SCN) in the hypothalamus is known as the body's master clock, orchestrating various physiological processes through a network of molecular and cellular mechanisms. The disruption of these circadian rhythms has been linked to various health issues, including sleep disorders, metabolic syndrome, and mood disorders. As researchers delve deeper into circadian signaling pathways, SCT recombinant proteins have emerged as vital tools for elucidating the mechanisms underlying circadian regulation. These proteins, produced through genetic engineering techniques, can be used to study the interactions between circadian genes and proteins, offering insights into how these factors influence behavior and physiology. By exploring the structural and functional characteristics of SCT proteins, scientists aim to better understand their role in maintaining circadian homeostasis and developing targeted therapies for circadian-related disorders. Furthermore, the application of SCT recombinant proteins in experimental models can lead to breakthroughs in chronotherapy, where timing is optimized for drug administration, enhancing therapeutic efficacy while minimizing side effects. Overall, the research on SCT recombinant proteins is paving the way for significant advancements in our understanding of circadian biology and its implications for health and disease.

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