Analytical Data
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基因名
TCP11L2
- Application
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别名
E430026E19Rik; MGC109402; MGC39016; MGC40368; RGD1307494; T complex 11 (mouse) like 2; T complex 11 like 2; T complex Protein 11 like Protein 2; T-complex Protein 11-like Protein 2; T11L2_HUMAN; TCP11L2; TCP11L2 t complex 11 (mouse) like 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N4U5
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表达区间
1-519 aa
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氨基酸序列
MPFNGEKQCV GEDQPSDSDS SRFSESMASL SDYECSRQSF ASDSSSKSSS PASTSPPRVV TFDEVMATAR NLSNLTLAHE IAVNENFQLK QEALPEKSLA GRVKHIVHQA FWDVLDSELN ADPPEFEHAI KLFEEIREIL LSFLTPGGNR LRNQICEVLD TDLIRQQAEH SAVDIQGLAN YVISTMGKLC APVRDNDIRE LKATGNIVEV LRQIFHVLDL MQMDMANFTI MSLRPHLQRQ LVEYERTKFQ EILEETPSAL DQTTEWIKES VNEELFSLSE SALTPGAENT SKPSLSPTLV LNNSYLKLLQ WDYQKKELPE TLMTDGARLQ ELTEKLNQLK IIACLSLITN NMVGAITGGL PELASRLTRI SAVLLEGMNK ETFNLKEVLN SIGIQTCVEV NKTLMERGLP TLNAEIQANL IGQFSSIEEE DNPIWSLIDK RIKLYMRRLL CLPSPQKCMP PMPGGLAVIQ QELEALGSQY ANIVNLNKQV YGPFYANILR KLLFNEEAMG KVDASPPTN
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分子量
58.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of the TCP11L2 (TCP1 Ring Complex Subunit 11-Like 2) recombinant protein has gained attention due to its potential role in cellular processes, including chaperone activity and the assembly of protein complexes. TCP11L2 is part of the TCP1/CCT (TriC) complex, which is crucial for the folding of newly synthesized proteins and the stabilization of protein structures. Abnormalities or mutations in this gene may contribute to various diseases, particularly those involving protein misfolding and aggregation. Furthermore, TCP11L2 has been implicated in cancer biology, wherein it may influence tumor cell proliferation and survival. Developing recombinant TCP11L2 allows researchers to investigate its structure-function relationship, assess its potential as a biomarker, and explore its therapeutic implications. The expression and purification of this protein are essential for functional assays, structural studies, and high-throughput screening approaches aimed at identifying small molecules or peptides that can modulate its activity. Understanding TCP11L2's interactions and mechanisms could unveil new insights into disease pathways and foster the development of novel therapeutic strategies targeting its function in cellular homeostasis.
