Analytical Data
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Gene name
TBX10
- Application
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Alternative Names
TBX10; TBX7; T-box transcription factor TBX10; T-box protein 10
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75333
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Expression Region
1-385 aa
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AA Sequence
MAAFLSAGLG ILAPSETYPL PTTSSGWEPR LGSPFPSGPC TSSTGAQAVA EPTGQGPKNP RVSRVTVQLE MKPLWEEFNQ LGTEMIVTKA GRRMFPPFQV KILGMDSLAD YALLMDFIPL DDKRYRYAFH SSAWLVAGKA DPATPGRVHF HPDSPAKGAQ WMRQIVSFDK LKLTNNLLDD NGHIILNSMH RYQPRFHVVF VDPRKDSERY AQENFKSFIF TETQFTAVTA YQNHRITQLK IASNPFAKGF RESDLDSWPV APRPLLSVPA RSHSSLSPCV LKGATDREKD PNKASASTSK TPAWLHHQLL PPPEVLLAPA TYRPVTYQSL YSGAPSHLGI PRTRPAPYPL PNIRADRDQG GLPLPAGLGL LSPTVVCLGP GQDSQ
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Molecular Weight
42.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TBX10 is a member of the T-box family of transcription factors, which play crucial roles in development and gene regulation. It is primarily expressed during embryogenesis, influencing the formation of various tissues, including bones and cartilage. Mutations in the TBX10 gene have been linked to several developmental disorders, including skeletal dysplasias, highlighting its importance in proper morphogenesis. Research into TBX10 recombinant proteins has gained traction as scientists seek to elucidate its function and regulatory mechanisms. These recombinant proteins facilitate detailed studies on TBX10's interactions with other proteins and DNA, aiding in the understanding of its role in transcriptional regulation. Furthermore, investigation into TBX10's structure and function may provide insights into the molecular basis of associated skeletal disorders, potentially paving the way for therapeutic interventions. Thus, the study of TBX10 recombinant proteins not only enhances our understanding of fundamental biological processes but also holds promise for advancing medical research related to developmental anomalies.
