Analytical Data
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基因名
TBL1Y
- Application
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别名
F-box-like/WD repeat-containing protein TBL1Y. Transducin beta-like protein 1Y. Transducin-beta-like protein 1. Y-linked
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BQ87
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表达区间
1-522 aa
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氨基酸序列
MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPSALISILQKGLQYVEAEISINKDGTVFDSRPIESLSLIVAVIPDVVQMRQQAFGEKLTQQQASAAATEASAMAKAATMTPAAISQQNPPKNREATVNGEENGAHEINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQGTGGIFEVCWNARGDKVGASASDGSVCVLDL
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分子量
57.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TBL1Y, or Tazarotene-induced gene 1, is a protein encoded by the TBL1Y gene located on the Y chromosome, playing a significant role in various biological processes, including spermatogenesis and embryonic development. The study of TBL1Y is particularly pertinent given its association with male fertility and potential implications in sex determination and reproductive health. Research indicates that TBL1Y may function as a transcriptional coactivator involved in the regulation of target genes critical for testis development and function. The significance of TBL1Y extends to the investigation of Y chromosome-linked disorders, such as male infertility syndromes, where mutations or deletions in TBL1Y can lead to adverse reproductive outcomes. Furthermore, TBL1Y's involvement in signaling pathways and cellular mechanisms enhances its relevance in understanding broader biological phenomena, including cancer progression and resistance to therapy in males. As a result, the exploration of TBL1Y not only contributes to the fields of genetics and reproductive biology but also opens avenues for potential therapeutic interventions aimed at addressing male infertility and associated conditions. Continuing research on TBL1Y is essential for elucidating its precise functions, regulatory mechanisms, and potential clinical applications.
