Analytical Data
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Gene name
TBC1D10C
- Application
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Alternative Names
1810062O14Rik; AI428527; Carabin; FLJ00332; MGC46488; RGD1311490; TB10C_HUMAN; TBC1 domain family member 10C; TBC1D10C
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IV04
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Expression Region
1-446 aa
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AA Sequence
MAQALGEDLV QPPELQDDSS SLGSDSELSG PGPYRQADRY GFIGGSSAEP GPGHPPADLI RQREMKWVEM TSHWEKTMSR RYKKVKMQCR KGIPSALRAR CWPLLCGAHV CQKNSPGTYQ ELAEAPGDPQ WMETIGRDLH RQFPLHEMFV SPQGHGQQGL LQVLKAYTLY RPEQGYCQAQ GPVAAVLLMH LPPEEAFWCL VQICEVYLPG YYGPHMEAVR LDAEVFMALL RRLLPHVHKH LQQVGVGPLL YLPEWFLCLF ARSLPFPTVL RVWDAFLSEG ARVLFRVGLT LVRLALGTAE QRGACPGLLE TLGALRAIPP AQLQEEAFMS QVHSVVLSER DLQREIKAQL AQLPDSAPGP PPRPQVRLAG AQAIFEAQQL AGVRRGAKPE VPRIVVQPPE EPRPPRRKPQ TRGKTFHGLL TRARGPPIEG PPRPQRGSTS FLDTRF
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Molecular Weight
49.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TBC1D10C is a member of the TBC1D family of proteins, which are known for their roles in regulating small GTPases involved in intracellular transport and membrane trafficking. The study of TBC1D10C has gained importance due to its potential involvement in various cellular processes, including endocytosis and exocytosis, as well as its implications in several pathological conditions such as cancer and metabolic disorders. Evidence suggests that TBC1D10C may be a critical regulator of the Rab family of small GTPases, influencing vesicle dynamics and cellular signaling pathways. Additionally, its expression patterns in different tissues and its interaction with other protein complexes have made it a focal point of research aimed at understanding the molecular mechanisms underlying cellular homeostasis. Given the complexity of membrane trafficking and its essential role in maintaining cellular functions, studying TBC1D10C through recombinant protein techniques can provide valuable insights into its specific functions and regulatory mechanisms. This could pave the way for the development of therapeutic strategies targeting the pathways modulated by TBC1D10C, contributing to advancements in the treatment of diseases associated with dysregulated vesicular transport.
