Analytical Data
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Gene name
WISP2
- Application
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Alternative Names
WISP2；CT58；CTGFL；WISP2；CCN family member 5
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O76076
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Expression Region
24-250aa
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AA Sequence
MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGFTCVP LCSEDVRLPS WDCPHPRRVE VLGKCCPEWV CGQGGGLGTQ PLPAQGPQFS GLVSSLPPGV PCPEWSTAWG PCSTTCGLGM ATRVSNQNRF CRLETQRRLC LSRPCPPSRG RSPQNSAF
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Molecular Weight
27 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
WISP2, or WNT1 inducible signaling pathway protein 2, is a member of the CCN family of secreted proteins, which play critical roles in cellular processes such as proliferation, differentiation, and migration. Researchers have focused on WISP2 due to its involvement in various physiological and pathological conditions, including cancer, fibrosis, and bone disorders. It is believed to modulate signaling pathways associated with Wnt and TGF-β, thereby influencing tissue development and repair. Studies have indicated that aberrant expression of WISP2 is linked to tumor progression and metastasis, highlighting its potential as a biomarker and therapeutic target in oncology. Recent investigations utilizing recombinant WISP2 proteins have provided insights into its functional mechanisms and interactions with cellular receptors, offering a deeper understanding of its role in cellular signaling. Furthermore, the production of recombinant WISP2 has facilitated the exploration of its structure-function relationships, advancing the knowledge of its biological activity. This research is poised to contribute to the development of novel treatment strategies targeting WISP2-related pathways, with the hope of improving outcomes in diseases where WISP2 plays a critical role. As the scientific community continues to unravel the complexities of WISP2, its potential as a therapeutic agent and a valuable tool in understanding cellular dynamics remains an exciting area of exploration.
