Analytical Data
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基因名
STX16
- Application
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别名
STX16; Syntaxin-16; Syn16
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O14662
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表达区间
1-304 aa
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氨基酸序列
MATRRLTDAFLLLRNNSIQNRQLLAEQLADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLVGVKSR
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分子量
61.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
STX16, a member of the syntaxin family of proteins, plays a crucial role in regulating membrane trafficking, particularly in the context of intracellular vesicle transport. Research on STX16 has gained significance due to its involvement in various cellular processes, including the fusion of vesicles with target membranes and the maintenance of cellular homeostasis. Dysregulation of STX16 has been implicated in several diseases, including neurodegenerative disorders and cancer, highlighting the importance of understanding its functional mechanisms. Recent studies have focused on the structural characteristics of STX16, its interaction with other SNARE (Soluble NSF Attachment Protein Receptor) proteins, and its role in specific cellular pathways, such as endocytosis and protein sorting. By employing techniques like recombinant protein expression and purification, researchers aim to elucidate the biochemical properties of STX16, paving the way for potential therapeutic interventions targeting STX16-mediated pathways. As the understanding of STX16 continues to evolve, it may offer new insights into the intricacies of cellular communication and the molecular underpinnings of diseases, reinforcing its significance in cell biology and medical research.
