Analytical Data
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基因名
ERVW-1
- Application
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别名
ERVW-1；ERVWE1；Syncytin-1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UQF0
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表达区间
21-443aa
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氨基酸序列
APPPCRCMTSSSPYQEFLWRMQRPGNIDAPSYRSLSKGTPTFTAHTHMPRNCYHSATLCMHANTHYWTGKMINPSCPGGLGVTVCWTYFTQTGMSDGGGVQDQAREKHVKEVISQLTRVHGTSSPYKGLDLSKLHETLRTHTRLVSLFNTTLTGLHEVSAQNPTNCWICLPLNFRPYVSIPVPEQWNNFSTEINTTSVLVGPLVSNLEITHTSNLTCVKFSNTTYTTNSQCIRWVTPPTQIVCLPSGIFFVCGTSAYRCLNGSSESMCFLSFLVPPMTIYTEQDLYSYVISKPRNKRVPILPFVIGAGVLGALGTGIGGITTSTQFYYKLSQELNGDMERVADSLVTLQDQLNSLAAVVLQNRRALDLLTAERGGTCLFLGEECCYYVNQSGIVTEKVKEIRDRIQRRAEELRNTGPWGLLSQ
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分子量
53.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ERVW-1 (Endogenous Retrovirus W-1) is a protein encoded by a human endogenous retroviral gene, which has garnered significant interest within the fields of virology, immunology, and cancer research. Emerging evidence suggests that ERVW-1 may play a role in modulating immune responses and influencing various pathophysiological processes. Specifically, it has been linked to immune evasion strategies utilized by tumors, as well as interactions with host immune cells that could alter the tumor microenvironment. Furthermore, studies have indicated that ERVW-1 might be involved in the regulation of pluripotency and differentiation in stem cells, highlighting its potential importance in developmental biology. Recent investigations have focused on the expression patterns of ERVW-1 in different tissues and its potential as a biomarker for various diseases, including malignancies. Understanding the functional roles of ERVW-1 may provide insights into the mechanisms of tumor progression and offer opportunities for developing novel therapeutic strategies. As research continues, elucidating the complex nature of ERVW-1 and its interactions with both the immune system and tumor biology remains a promising avenue for advancing our knowledge in these interconnected fields.
