Analytical Data
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Gene name
SRCRB4D
- Application
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Alternative Names
SSC4D; SRCRB4DScavenger receptor cysteine-rich domain-containing group B protein; Four scavenger receptor cysteine-rich domains-containing protein; S4D-SRCRB
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8WTU2
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Expression Region
48-575aa
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AA Sequence
LQP TPLPFQELRL VGGPSRCRGR LEVMHGGSWG SVCDDDWDVV DANVVCRQLG CGLALPVPRP LAFGQGRGPI LLDNVECRGQ EAALSECGSR GWGVHNCFHY EDVAVLCDEF LPTQPPTRKM LTSRAPPTTL PNGKSEGSVR LVGGANLCQG RVEILHSGLW GTVCDDDWGL PDAAVVCRQL GCGAAMAATT NAFFGYGTGH ILLDNVHCEG GEPRLAACQS LGWGVHNCGH HEDAGALCAG LGPPTLTALP SSATREDWAW QTDPSATGVG PQPSRETALL TTAAWAAGKK SGRLRLVGGP GPCRGRVEVL HAGGWGTVCD DDWDFADARV ACREAGCGPA LGATGLGHFG YGRGPVLLDN VGCAGTEARL SDCFHLGWGQ HNCGHHEDAG ALCAGPEELG LQVQQDGSET TRVPTPRPRD GHLRLVNGAH RCEGRVELYL GQRWGTVCDD AWDLRAAGVL CRQLGCGQAL AAPGEAHFGP GRGPILLDNV KCRGEESALL LCSHIRWDAH NCDHSEDASV LCQPS
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Molecular Weight
60.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The SRCRB4D protein, a member of the scavenger receptor cysteine-rich (SRCR) superfamily, has garnered attention in the field of molecular biology due to its potential roles in immune response and cell adhesion processes. This protein is characterized by its unique domain structure, which includes conserved cysteine residues that are thought to play crucial roles in ligand binding and interaction with various protein partners. Research has indicated that SRCRB4D may be involved in important biological functions such as pathogen recognition and the modulation of inflammatory responses, making it a key target for understanding disease mechanisms, particularly in autoimmune and infectious diseases. Studies have also suggested that variation in SRCRB4D expression levels can influence susceptibility to infections and inflammatory conditions, highlighting its potential as a biomarker for disease progression. The exploration of SRCRB4D and its functional properties holds promise not only for advancing our understanding of immune regulation but also for the development of novel therapeutic strategies aimed at modulating immune responses in chronic diseases. As researchers delve deeper into the biology of SRCRB4D, the protein is expected to reveal further insights into the complexities of cellular interactions and signaling pathways within the immune system.
