Cat: PA1000-7913

Recombinant Human SCXB Protein,His

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Analytical Data

  • Gene name

    SCXB

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    SCXB;BHLHA41;BHLHA48;SCXA;Basic helix-loop-helix transcription factor scleraxis

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q7RTU7

  • Expression Region

    1-201aa

  • AA Sequence

    MSFATLRPAP PGRYLYPEVS PLSEDEDRGS DSSGSDEKPC RVHAARCGLQ GARRRAGGRR AGGGGPGGRP GREPRQRHTA NARERDRTNS VNTAFTALRT LIPTEPADRK LSKIETLRLA SSYISHLGNV LLAGEACGDG QPCHSGPAFF HAARAGSPPP PPPPPPARDG ENTQPKQICT FCLSNQRKLS KDRDRKTAIR S

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

SCXB, or subcutaneous fat cell-expressed protein B, is a member of the S100 protein family, which is known for its role in various cellular processes, including inflammation, cell differentiation, and apoptosis. Recent studies have highlighted its potential involvement in metabolic regulation and tissue homeostasis, particularly in the context of adipocyte function and obesity-related diseases. The dysregulation of SCXB has been linked to altered lipid metabolism and insulin resistance, making it a significant target for investigating therapeutic approaches for metabolic syndromes. Research has focused on characterizing the structure and function of SCXB, understanding its signaling pathways, and exploring its interaction with other proteins and cells in the adipose tissue microenvironment. Additionally, the examination of SCXB gene expression in various physiological and pathological conditions has provided insights into its role in obesity and related complications, such as Type 2 diabetes and cardiovascular diseases. The findings suggest that SCXB could serve as a biomarker for obesity and a potential therapeutic target, paving the way for new strategies in the management and treatment of metabolic disorders. Overall, the ongoing research into SCXB holds promise for advancing our understanding of fat biology and its implications for health and disease.

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