Analytical Data
-
Gene name
Commd5
- Application
-
Alternative Names
Commd5；COMM domain-containing Protein 5
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9GZQ3
-
Expression Region
2-224aa
-
AA Sequence
SAVGAATPYLHHPGDSHSGRVSFLGAQLPPEVAAMARLLGDLDRSTFRKLLKFVVSSLQGEDCREAVQRLGVSANLPEEQLGALLAGMHTLLQQALRLPPTSLKPDTFRDQLQELCIPQDLVGDLASVVFGSQRPLLDSVAQQQGAWLPHVADFRWRVDVAISTSALARSLQPSVLMQLKLSDGSAYRFEVPTAKFQELRYSVALVLKEMADLEKRCERRLQD
-
Molecular Weight
29.5 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Commd5 is a protein that plays a pivotal role in various cellular processes, particularly in the regulation of protein degradation and cellular signaling pathways. It is a member of the COMM domain-containing protein family, characterized by their involvement in the modulation of ubiquitin-proteasome pathways. Researchers have identified Commd5 as a critical component in maintaining cellular homeostasis, influencing processes such as metal ion transport, inflammatory responses, and cell proliferation. Alterations in Commd5 expression have been associated with a range of diseases, including cancer and inflammatory disorders, highlighting its potential as a therapeutic target. The study of Commd5's structure and function has gained significant attention as it may provide insights into its role in disease mechanisms and aid in the development of novel treatments. By understanding the molecular interactions and pathways mediated by Commd5, scientists aim to leverage this knowledge for potential clinical applications, making it an important focus in the fields of molecular biology and pharmacology. Overall, the ongoing research on Commd5 is poised to unveil its significance in health and disease, paving the way for innovative strategies to combat various pathological conditions.
