Analytical Data
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Gene name
SPATA12
- Application
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Alternative Names
SPATA12; SRG5; Spermatogenesis-associated protein 12; Spermatogenesis-related protein 5
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7Z6I5
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Expression Region
1-190 aa
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AA Sequence
MSSSALTCGS TLEKSGDTWE MKALDSSRLV PWPPRGLGSS TQHPNKPHCA LASCQGPGVL PGAASALPEL TFQGDVCQSE TCQRYLQAAI SLDIAVSQIN LLGRPSSPPA LLIQQGSCEQ VIHNSTPQFL GMEDGDNERT TGWLWRLCED IDAEPSSTGC SRSNQLTFTE GCFVRSLSTV YSNTHIHTHL
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Molecular Weight
20.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SPATA12, also known as sperm-associated antigen 12, has garnered attention in recent years due to its potential role in male fertility and reproductive health. This protein, initially identified in the testis, is believed to be involved in the maturation and function of spermatozoa. Research indicates that SPATA12 may be critical for the development of spermatogenic cells and the regulation of sperm motility, which are essential factors for successful fertilization. The understanding of its function has implications not only for basic reproductive biology but also for clinical applications, particularly in diagnosing and treating male infertility. Additionally, as a testis-specific protein, SPATA12 holds promise as a molecular marker in testicular cancer and other reproductive disorders. However, the precise molecular mechanisms underpinning its action remain largely unexplored. Recent advances in recombinant protein technology have facilitated the purification and characterization of SPATA12, enabling researchers to investigate its biological properties and interactions in more detail. This progress is crucial for establishing SPATA12's potential as a biomarker or therapeutic target in reproductive medicine. As the field of reproductive biology continues to evolve, understanding the complexities of proteins like SPATA12 could lead to novel insights into male reproductive health and new strategies for addressing infertility.
