Analytical Data
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基因名
RMND5A
- Application
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别名
RMND5A；E3 ubiquitin-Protein transferase RMND5A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H871
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表达区间
1-385aa
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氨基酸序列
MDQCVTVERELEKVLHKFSGYGQLCERGLEELIDYTGGLKHEILQSHGQDAELSGTLSLVLTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRLLNEVMVEHFFRQGMLDVAEELCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVSNREMLIAQNSSLEFKLHRLYFISLLMGGTTNQREALQYAKNFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQSPGD
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分子量
59.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RMND5A, a member of the RWD domain-containing protein family, has gained attention due to its potential role in various biological processes, including ribosomal assembly, mitochondrial function, and cellular stress responses. Research indicates that RMND5A is crucial for the maturation of ribosomal RNA and the assembly of ribosomal subunits, which are essential for protein synthesis in cells. Additionally, mutations or dysregulation of RMND5A have been linked to several diseases, including neurodevelopmental disorders and certain cancers, highlighting its importance in human health. The increasing interest in RMND5A has prompted investigations into its structure and function, particularly through the study of recombinant RMND5A proteins. These studies aim to elucidate the molecular mechanisms underlying RMND5A's role in cellular processes and its interactions with other proteins, thus paving the way for potential therapeutic applications. Furthermore, understanding the functional aspects of RMND5A may contribute to the development of strategies to target its pathways in disease management. As research continues, the characterization of RMND5A recombinant proteins serves as a crucial step toward delineating its biological significance and therapeutic potential.
