Analytical Data
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Gene name
TCHP
- Application
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Alternative Names
TCHP;Trichoplein keratin filament-binding Protein
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BT92
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Expression Region
1-498aa
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AA Sequence
MALPTLPSYWCSQQRLNQQLARQREQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKTSYQRSMHAYQREKMKEEKRRSLEARREKLRQLMQEEQDLLARELEELRLSMNLQERRIREQHGKLKSAKEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATAEQENKRYENEYERARREALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLARREQVMADVAWMKQAIEEQLQLERAREAELQMLLREEAKEMWEKREAEWARERSARDRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRELARREKEESEKLKSARKQELEAQVAERRLQAWEADQQEEEEEEEARRVEQLSDALLQQEAETMAEQGYRPKPYGHPKIAWN
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Molecular Weight
77.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TCHP (T cell-derived cytokine homologue protein) is an important protein involved in immune regulation and has garnered significant research interest due to its potential therapeutic applications. Emerging studies have indicated that TCHP plays a crucial role in modulating T cell activity, influencing the immune response in various conditions, including autoimmune diseases, cancer, and infections. The characterization and understanding of TCHP's structure and function are pivotal for developing targeted therapies that can enhance or suppress immune responses as needed. Researchers are particularly focused on the recombinant expression of TCHP to elucidate its biological activities and interactions at the molecular level. By employing techniques such as genetic engineering and protein purification, scientists aim to produce high-yield, functional TCHP for further investigation. This protein's unique properties could lead to novel strategies for immunotherapy, providing new avenues for treating challenging health issues. As the field of immunology advances, the study of TCHP and its functionalities holds promise for the development of innovative treatments aimed at fine-tuning immune responses for better clinical outcomes.











