Analytical Data
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基因名
DDX55
- Application
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别名
ATP dependent RNA helicase DDX55; ATP-dependent RNA helicase DDX55; DDX 55; ddx55; DDX55_HUMAN; DEAD box protein 55; FLJ16577; KIAA1595; MGC33209
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NHQ9
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表达区间
1-207aa
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氨基酸序列
MKPQRNTADLLPKLKSMALADRAVFEKGMKAFVSYVQAYAKHECNLIFRLKDLDFASLARGFALLRMPKMPELRGKQFPDFVPVDVNTDTIPFKDKIREKQRQKLLEQQRREKTENEGRRKFIKNKAWSKQKAKKEKKKKMNEKRKREEGSDIEDEDMEELLNDTRLLKKLKKGKITEEEFEKGLLTTGKRTIKTVDLGISDLEDDC
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分子量
50.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DDX55, a member of the DEAD-box RNA helicase family, plays a pivotal role in various cellular processes, including RNA metabolism, gene expression regulation, and ribosome biogenesis. Its dysfunction has been implicated in several diseases, particularly in the context of cancer, where altered RNA processing can lead to malignant transformation. Recent studies have highlighted the significance of DDX55 in facilitating the unwinding of RNA structures, thereby influencing mRNA stability and translation efficiency. Given its essential functions, there is a growing interest in investigating DDX55 as a potential therapeutic target. Recombinant DDX55 protein production is crucial for understanding its biochemical properties, interactions with RNA, and effects in disease models. By generating and characterizing this recombinant protein, researchers aim to elucidate the molecular mechanisms underlying DDX55 activity and its role in pathological conditions, ultimately contributing to the development of novel therapeutic strategies. This research holds promise not only for advancing our understanding of RNA helicases but also for the potential exploitation of DDX55 in therapeutic applications.
