Cat: PAX2000-11556

Recombinant Human SNX29 Protein,GST

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Analytical Data

  • Gene name

    SNX29

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    SNX29; RUNDC2A; Sorting nexin-29; RUN domain-containing protein 2A

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8TEQ0

  • Expression Region

    1-456 aa

  • AA Sequence

    MARIRDLYFVAVFFHLRPLEGNTCLSQMHSWAPLKVLHNDSDILFPVSGVGSYSPADAPLGSLENGTGPEDHVLPDPGLRYSVEASSPGHGSPLSSLLPSASVPESMTISELRQATVAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEVDTLKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEAVPNLWSVDGEVTVAEQKPGEIAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAIGNKDAKFVEERRKQLQNYLRSVMNKVIQMVPEFAASPKKETLIQLMPFFVDITPPGEPVNSRPKAASRFPKLSRGQPRETRNVEPQSGDL

  • Molecular Weight

    50.2 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

SNX29, a member of the sorting nexin family, plays a critical role in intracellular trafficking, particularly in endosomal sorting and recycling processes. Recent research has highlighted its involvement in the regulation of membrane protein localization and function, which is pivotal for maintaining cellular homeostasis and signal transduction. Studies have indicated that SNX29 interacts with various proteins and cellular pathways, suggesting its potential role in diverse physiological and pathological contexts, including neurodegenerative diseases and cancer. The investigation of SNX29 recombinant proteins has become essential for elucidating its molecular mechanisms and functional implications. By producing and characterizing SNX29 in a controlled laboratory environment, researchers aim to explore its structural properties, interactions, and effects on cellular systems. This research not only enhances the understanding of SNX29’s biological significance but also opens avenues for therapeutic development targeting SNX29-related pathways, potentially leading to novel strategies for treating diseases linked to endosomal dysregulation.

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