Analytical Data
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Gene name
SNX22
- Application
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Alternative Names
SNX22; Sorting nexin-22
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96L94
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Expression Region
1-193 aa
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AA Sequence
MLEVHIPSVG PEAEGPRQSP EKSHMVFRVE VLCSGRRHTV PRRYSEFHAL HKRIKKLYKV PDFPSKRLPN WRTRGLEQRR QGLEAYIQGI LYLNQEVPKE LLEFLRLRHF PTDPKASNWG TLREFLPGDS SSQQHQRPVL SFHVDPYVCN PSPESLPNVV VNGVLQGLYS FSISPDKAQP KAACHPAPLP PMP
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Molecular Weight
22.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SNX22 (Sorting Nexin 22) is a member of the sorting nexin family, which plays a crucial role in intracellular trafficking and membrane dynamics. This protein is particularly associated with endosomal and lysosomal pathways, where it aids in the sorting and recycling of various membrane proteins. Research into SNX22's functions has gained significance due to its involvement in physiological processes such as nutrient sensing, ion homeostasis, and cellular signaling. Additionally, recent studies have suggested a potential link between SNX22 and various diseases, including neurodegenerative conditions and metabolic disorders, highlighting its importance in maintaining cellular health. Given these insights, the characterization and functional analysis of SNX22 recombinant proteins have become a focal point in molecular biology and biomedical research, enabling scientists to better understand its mechanisms of action and potential therapeutic applications. By studying SNX22 in detail, researchers hope to elucidate its role in cellular pathways and potentially develop targeted therapies for diseases associated with its dysfunction.
