Analytical Data
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Gene name
SNX21
- Application
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Alternative Names
SNX21; C20orf161; SNXL; Sorting nexin-21; Sorting nexin L; SNX-L
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q969T3
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Expression Region
1-373 aa
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AA Sequence
MHRGTQEGAM ASRLLHRLRH ALAGDGPGEA AASPEAEQFP ESSELEDDDA EGLSSRLSGT LSFTSAEDDE DDEDEDDEEA GPDQLPLGDG TSGEDAERSP PPDGQWGSQL LARQLQDFWK KSRNTLAPQR LLFEVTSANV VKDPPSKYVL YTLAVIGPGP PDCQPAQISR RYSDFERLHR NLQRQFRGPM AAISFPRKRL RRNFTAETIA RRSRAFEQFL GHLQAVPELR HAPDLQDFFV LPELRRAQSL TCTGLYREAL ALWANAWQLQ AQLGTPSGPD RPLLTLAGLA VCHQELEDPG EARACCEKAL QLLGDKSLHP LLAPFLEAHV RLSWRLGLDK RQSEARLQAL QEAGLTPTPP PSLKELLIKE VLD
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Molecular Weight
41.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SNX21 (Sorting Nexin 21) is a member of the sorting nexin family, which regulates intracellular trafficking and membrane dynamics. The protein plays a crucial role in the endosomal-lysosomal pathway, influencing protein sorting, recycling, and degradation processes. Recent studies have highlighted SNX21's involvement in various cellular functions, including endocytosis and autophagy, as well as its potential implications in disease mechanisms, particularly in neurodegenerative disorders and cancer. Understanding the structure and function of SNX21 is essential for elucidating its role in cellular homeostasis and pathogenesis. The study of SNX21 recombinant protein facilitates detailed investigations into its molecular interactions and mechanisms of action, which may lead to the development of novel therapeutic strategies targeting related conditions. Given the increasing recognition of membrane trafficking processes in health and disease, research into SNX21 and its associated pathways presents significant potential for advancing our understanding of cellular biology and developing innovative treatments.
