Analytical Data
-
Gene name
SNAPC5
- Application
-
Alternative Names
SNAPC5; SNAP19snRNA-activating protein complex subunit 5; SNAPc subunit 5; Small nuclear RNA-activating complex polypeptide 5; snRNA-activating protein complex 19 kDa subunit; SNAPc 19 kDa subunit
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
O75971
-
Expression Region
1-98 aa
-
AA Sequence
MLSRLQELRK EEETLLRLKA ALHDQLNRLK VEELALQSMI SSRRGDEMLS SHTVPEQSHD MLVHVDNEAS INQTTLELST KSHVTEEEEE EEEEESDS
-
Molecular Weight
11.3 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SNAPC5 is a crucial component of the small nuclear RNA-activated protein complex (SNAP) that plays a vital role in the biogenesis of spliceosomal small nuclear RNAs (snRNAs). This protein is essential for the maturation and processing of pre-mRNA transcripts in eukaryotic cells, contributing significantly to the regulation of gene expression. Research into SNAPC5 has gained momentum due to its implications in various cellular processes, including RNA splicing, and its potential connection to several diseases, such as cancer and neurodegenerative disorders. Studies have shown that alterations in SNAPC5 levels or function can disrupt normal splicing mechanisms, leading to aberrant gene expression patterns. Furthermore, understanding SNAPC5's structure and interactions within the spliceosomal complex can provide insights into the broader mechanisms of RNA processing and identify potential therapeutic targets. As a result, SNAPC5 becomes a focus of interest for molecular biology and biomedicine, with ongoing investigations seeking to unravel its regulatory functions and the molecular consequences of its dysregulation.
