Analytical Data
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基因名
SMTNL2
- Application
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别名
SMTNL2; Smoothelin-like protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q2TAL5
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表达区间
1-461 aa
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氨基酸序列
MEPAPDAQEA RTVREALGRY ELEGAVRA LHEDMRGLQR GVERRVAEAM RLAGPLARTV ADLQRDNQRL QAQLERLTRQ VEALGLASGM SPVPGTPGTP SPPPAPGVPD RAPRLGSARF ASHATFSLSG RGQSLDHDEA SESEMRKTSN SCIMENGHQP GAGPGDGPPE IAQNFSAPDP PRPRPVSLSL RLPHQPVTAI TRVSDRFSGE TSALSPMS TLGGLNPS PSEVITPWTP SPSEKNSSFT WSVPSSGYGA VTASKHSNSP PLVTPPQSPV SPQPPAITQV HRQGERRREL VRSQTLPRTS EAQARKALFE KWEQETGK GKGEARARLK RSQSFGVASA SSIKQILLEW CRSKTLGYQH VDLQNFSSSW SDGMAFCALV HSFFPDAFDY NSLSPTQRQK NFELAFTMAE NLANCERLIE VEDMMVMGRK PDPMCVFTYV QSLYNHLRRF E
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分子量
50.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SMTNL2, or Smoothelin-like protein 2, is a member of the smoothelin family, which is primarily expressed in smooth muscle tissues. Recent research has highlighted its role in various physiological and pathological processes, including muscle contraction, cell signaling, and tissue development. SMTNL2 has gained attention for its potential involvement in cardiovascular diseases and gastrointestinal disorders due to its expression in vascular smooth muscle and gastrointestinal smooth muscle. Studies have indicated that SMTNL2 is implicated in cellular mechanotransduction, where cells convert mechanical stimuli into biochemical signals, an essential process for maintaining tissue homeostasis. Furthermore, its role in regulating the cytoskeleton suggests that SMTNL2 may influence cell shape and motility. Given these functions, the recombinant production of SMTNL2 protein is crucial for elucidating its mechanisms of action and therapeutic potential. Researchers aim to employ recombinant SMTNL2 to study its biochemical properties, interaction with other proteins, and potential regulatory pathways. This foundational knowledge could pave the way for novel therapeutic strategies targeting SMTNL2 in diseases linked to smooth muscle dysfunction. Overall, understanding SMTNL2's biological importance and molecular interactions through recombinant technology can contribute significantly to the fields of cardiovascular research and gastrointestinal health.












