Analytical Data
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基因名
FMR1NB
- Application
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别名
FMR1NB;FMR1 neighbor Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N0W7
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表达区间
90-183aa
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氨基酸序列
LCSGSSYFVLANGHILPNSENAHGQSLEEDSALEALLNFFFPTTCNLRENQVAKPCNELQDLSESECLRHKCCFSSSGTTSFKCFAPFRDVPKQ
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分子量
15.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FMR1NB (Fragile X Mental Retardation 1 Neighboring Gene) is a gene that has garnered attention in the realm of genetic research due to its potential role in neurodevelopmental disorders. Located adjacent to the FMR1 gene, which is famously associated with Fragile X syndrome, FMR1NB is believed to be involved in the regulation of various cellular processes and may impact neuronal function. Recent studies have suggested that FMR1NB could play a critical role in modulating synaptic plasticity, a key mechanism underlying learning and memory. The understanding of FMR1NB's function is still in its early stages, but it may also contribute to the broader spectrum of psychiatric and neurodevelopmental disorders beyond Fragile X syndrome itself. Researchers are investigating the mechanisms by which FMR1NB influences neuronal behavior, its interactions with other key proteins, and its expression patterns during brain development. The recombinant protein derived from FMR1NB is being studied for its potential applications in understanding the pathophysiology of related disorders and may lead to the identification of new therapeutic targets. As such, FMR1NB serves as a promising candidate for further exploration in the context of neurobiology, genetics, and therapeutic development. Understanding its role could provide deeper insights into the molecular underpinnings of critical neurodevelopmental processes and pave the way for interventions targeting related disorders.












