Analytical Data
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基因名
SLC34A1
- Application
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别名
Sodium-dependent phosphate transport protein 2A. Sodium-phosphate transport protein 2A. Na(+)-dependent phosphate cotransporter 2A. NaPi-3. Sodium/phosphate cotransporter 2A. Na(+)/Pi cotransporter 2A. NaPi-2a. Solute carrier family 34 member 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q06495
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表达区间
1-639 aa
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氨基酸序列
MLSYGERLGSPAVSPLPVRGGHVMRGTAFAYVPSPQVLHRIPGTSAYAFPSLGPVALAEHTCPCGEVLERHEPLPAKLALEEEQKPESRLVPKLRQAGAMLLKVPLMLTFLYLFVCSLDMLSSAFQLAGGKVAGDIFKDNAILSNPVAGLVVGILVTVLVQSSSTSTSIIVSMVSSGLLEVSSAIPIIMGSNIGTSVTNTIVALMQAGDRTDFRRAFAGATVHDCFNWLSVLVLLPLEAATGYLHHITRLVVASFNIHGGRDAPDLLKIITEPFTKLIIQLDESVITSIATGDESLRNHSLIQIWCHPDSLQAPTSMSRAEANSSQTLGNATMEKCNHIFVDTGLPDLAVGLILLAGALVLLCTCLILLVKMLNSLLKGQVAKVIQKVINTDFPAPFTWVTGYFAMVVGASMTFVVQSSSVFTSAITPLIGLGVISIERAYPLTLGSNIGTTTTAILAALASPREKLSSAFQIALCHFFFNISGILLWYPVPCTRLPIRMAKALGKRTAKYRWFAVLYLLVCFLLLPSLVFGISMAGWQVMVGVGTPFGALLAFVVLINVLQSRSPGHLPKWLQTWDFLPRWMHSLKPLDHLITRATLCCARPEPRSPPLPPRVFLEELPPATPSPRLALPAHHNATRL
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分子量
95.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC34A1, a member of the solute carrier family 34, encodes a sodium-dependent phosphate transporter primarily expressed in the kidneys and intestine. This protein plays a crucial role in regulating phosphate homeostasis, which is essential for various physiological processes, including bone mineralization and cellular metabolism. Mutations in the SLC34A1 gene are associated with hereditary hypophosphatemic rickets and other phosphate-related disorders, highlighting its significance in human health. Research on SLC34A1 recombinant proteins aims to elucidate its transport mechanisms, functional characteristics, and interaction with other cellular components. Advances in this area could lead to novel therapeutic strategies for managing phosphate imbalances and associated diseases. The production and characterization of SLC34A1 recombinant proteins not only provide insights into its molecular structure and function but also facilitate the development of assays for drug screening and the exploration of potential inhibitors or activators. Understanding the intricacies of SLC34A1 could ultimately contribute to improved treatment options for patients suffering from conditions linked to phosphate dysregulation.
