Cat: PA2000-3272

Recombinant Human RMDN3 Protein,His

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Analytical Data

  • Gene name

    RMDN3

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    RMDN3;Vesicle-associated membrane Protein-associated Protein B/C

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q96TC7

  • Expression Region

    1-470aa

  • AA Sequence

    MSRLGALGGARAGLGLLLGTAAGLGFLCLLYSQRWKRTQRHGRSQSLPNSLDYTQTSDPGRHVMLLRAVPGGAGDASVLPSLPREGQEKVLDRLDFVLTSLVALRREVEELRSSLRGLAGEIVGEVRCHMEENQRVARRRRFPFVRERSDSTGSSSVYFTASSGATFTDAESEGGYTTANAESDNERDSDKESEDGEDEVSCETVKMGRKDSLDLEEEAASGASSALEAGGSSGLEDVLPLLQQADELHRGDEQGKREGFQLLLNNKLVYGSRQDFLWRLARAYSDMCELTEEVSEKKSYALDGKEEAEAALEKGDESADCHLWYAVLCGQLAEHESIQRRIQSGFSFKEHVDKAIALQPENPMAHFLLGRWCYQVSHLSWLEKKTATALLESPLSATVEDALQSFLKAEELQPGFSKAGRVYISKCYRELGKNSEARWWMKLALELPDVTKEDLAIQKDLEELEVILRD

  • Molecular Weight

    56.1 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

RMDN3, or RMDN3 GTPase, is a member of the Ras superfamily of small GTPases, which are critically involved in various cellular processes, including signal transduction, cytoskeletal dynamics, and cellular proliferation. The study of RMDN3 has gained attention due to its role in neuronal development and its potential implications in neurological disorders. Recent research indicates that RMDN3 may influence neuronal differentiation and synaptic formation, making it a significant focus in neurobiology. Furthermore, alterations in RMDN3 expression have been associated with various malignancies, suggesting that it could serve as a biomarker or therapeutic target in cancer research. Investigating the molecular mechanisms of RMDN3, including its interactions with other proteins and its regulatory pathways, is essential for understanding its function in both normal physiology and disease states. Thus, the development of recombinant RMDN3 protein facilitates detailed studies on its biochemical properties and interactions, potentially revealing new insights into its roles in health and disease.

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