Cat: PAX2000-11392

Recombinant Human SLC25A31 Protein,GST

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Analytical Data

  • Gene name

    SLC25A31

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    SLC25A31; AAC4; ANT4; SFEC; ADP/ATP translocase 4; ADP.ATP carrier protein 4; Adenine nucleotide translocator 4; ANT 4; Solute carrier family 25 member 31; Sperm flagellar energy carrier protein

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9H0C2

  • Expression Region

    1-315 aa

  • AA Sequence

    MHREPAKKKAEKRLFDASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVLYDKIKEFFHIDIGGR

  • Molecular Weight

    61.4 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

SLC25A31, a member of the SLC25 family of mitochondrial transport proteins, plays a crucial role in cellular metabolism by facilitating the transport of key metabolites across the mitochondrial membrane. This protein is involved in the exchange of important molecules such as nucleotides and is essential for maintaining mitochondrial function, which is vital for ATP production and overall cellular energy homeostasis. Dysregulation or mutations in the SLC25A31 gene have been linked to various metabolic disorders, highlighting its significance in human health. Recent studies have focused on the characterization of the recombinant SLC25A31 protein to understand its structural and functional properties better. Recombinant protein synthesis allows for the production of ample quantities of SLC25A31 for biochemical assays, helping to elucidate its transport mechanisms and substrate specificity. This research is pivotal in identifying the therapeutic potential of targeting SLC25A31 in metabolic diseases and contributes to the broader understanding of mitochondrial biology. Exploring the interactions of SLC25A31 with other mitochondrial components may also reveal insights into its regulatory roles and the implications of its dysfunction in disease contexts, thereby representing a promising avenue for future therapeutic interventions.

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