Analytical Data
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Gene name
BMPRIA
- Application
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Alternative Names
BMPRIA；receptor Protein serine/threonine kinase
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P36894
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Expression Region
24-152aa
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AA Sequence
QNLDSMLHGT GMKSDSDQKK SENGVTLAPE DTLPFLKCYC SGHCPDDAIN NTCITNGHCF AIIEEDDQGE TTLASGCMKY EGSDFQCKDS PKAQLRRTIE CCRTNLCNQY LQPTLPPVVI GPFFDGSIR
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Molecular Weight
14 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BMPRIA, or Bone Morphogenetic Protein Receptor Type IA, is a member of the transforming growth factor-beta (TGF-β) superfamily and plays a crucial role in bone and cartilage development, as well as in the regulation of various cellular processes including proliferation, differentiation, and apoptosis. The study of BMPRIA and its recombinant protein has gained significant attention in recent years due to its potential therapeutic applications. Abnormal BMPRIA signaling has been associated with various pathologies, including osteoporosis, fibrodysplasia ossificans progressiva, and certain cancers, highlighting the importance of understanding its molecular mechanisms. Recombinant BMPRIA proteins can be utilized in biochemical assays and in vitro studies to elucidate its function in cell signaling pathways. Furthermore, these proteins hold promise for regenerative medicine, as they could possibly enhance bone regeneration and repair processes. Research on BMPRIA has also sparked interest in drug development, as targeting its pathway may offer novel strategies for treating musculoskeletal diseases and other conditions linked to dysregulated bone metabolism. Hence, the investigation into the structure, function, and potential applications of BMPRIA recombinant proteins continues to be a vital area of research in the field of biomedicine.
