Analytical Data
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基因名
GPR15L
- Application
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别名
GPR15L;C10orf99;GPR15L;Protein GPR15LG
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6UWK7
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表达区间
25-81aa
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氨基酸序列
KRRPAKAWSGRRTRLCCHRVPSPNSTNLKGHHVRLCKPCKLEPEPRLWVVPGALPQV
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分子量
14.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GPR15L, also known as G protein-coupled receptor 15-like, is a protein that plays a critical role in the immune system and is primarily involved in the regulation of T cell trafficking, particularly in the context of inflammatory and autoimmune diseases. It has surfaced as a significant factor in HIV pathogenesis, as it serves as a co-receptor for HIV entry into cells. The study of GPR15L recombinant proteins has garnered attention for its potential in elucidating the mechanisms that govern T cell localization and response during viral infections and immune responses. Researchers are focused on characterizing the structural and functional properties of GPR15L to understand its interactions with various ligands and receptors, which could pave the way for novel therapeutic strategies targeting immune-related disorders and HIV. The ability to produce GPR15L as a recombinant protein allows for detailed biochemical analyses, including binding studies and functional assays, which are essential in developing a comprehensive understanding of its role in immunology and virology. Increasing knowledge about GPR15L may lead to innovative approaches in treating diseases associated with T cell dysregulation and offers insights into potential vaccine development against HIV. Consequently, the investigation of GPR15L recombinant proteins presents an important avenue for research in both basic and applied biomedical sciences, aiming to leverage the protein's unique properties for therapeutic applications.












