Analytical Data
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基因名
CAMK1D
- Application
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别名
CAMK1D；CAMKKA；Calcium/calmodulin-dependent Protein kinase kinase 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IU85
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表达区间
1-385aa
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氨基酸序列
MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGL EFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVL DIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTH PDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIA WPLQGWQATFGGGDHPPKSDLVPRGSMARENGESSSSWKKQAEDIKKIFE FKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLR KIKHENIVALEDIYESPNHLYLVMQ LVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPEN LLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYS KAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDIS DSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRK NFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCLA PSTLCSFISSSSGVSGVGAERRPRPTTVTAVHSGSK
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分子量
69 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CAMK1D, or Calcium/Calmodulin-dependent protein kinase type 1D, is a member of the calcium/calmodulin-dependent protein kinase family that plays a crucial role in various cellular processes, including calcium signaling, cell proliferation, and differentiation. The significance of CAMK1D has garnered attention due to its involvement in diverse physiological and pathological conditions, such as neurogenesis, heart disease, and cancer. Recent studies have suggested that CAMK1D may act as a potential therapeutic target, as its expression levels and activity have been linked to the progression of certain tumors and neurological disorders. The recombinant expression of CAMK1D protein can provide a valuable tool for understanding its molecular mechanisms, interactions, and functional roles in cellular pathways. By producing this protein in a controlled recombinant system, researchers can examine its enzymatic properties, study protein-protein interactions, and identify specific substrates. Additionally, this research can facilitate the development of small molecule inhibitors or modulators that target CAMK1D for therapeutic interventions, thereby broadening our understanding of calcium-dependent signaling networks and their implications in health and disease. Thus, investigating the recombinant CAMK1D protein holds promise for advancing both basic biological knowledge and potential clinical applications.
