Analytical Data
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Gene name
CNBD1
- Application
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Alternative Names
CNBD1; CNBD1_HUMAN; Cyclic nucleotide-binding domain-containing protein 1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8NA66
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Expression Region
1-436aa
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AA Sequence
MPMSSLPAAILSHMTAINNVPPPPLHSIPNLKKSKHINYGQLNALCHIRGQHSRSMSNILSAHDTFMKQYPKVFLHQKPRLPKLFKQEEQRELNEGKEESQHQQPDDSNNIAVHVQRAHGGHILYRPKRATEKFEEFLAILKKLPIHRTPYEHKTVWKFLKTIPDLTFQLNDKHLKTLSKTVFSETWLKGSTVVANDGFYVILKGLARPQTNVYKNLIEGSDSPDSFISQSFHSFIWSEEFKNSTLAEMYLPSYDSMLSKWSTFGTLEVMPQNESETQMFSVVTEDDCEILKIPAKGYAKIKEEKIKLENMQKLKLIRMCPYYEEWPTLSIYELIALLKWKKFPPGHVIVESGNIISFVGYINSGCCNIYRSIIGFVKLRSNKVKRSQKLVYMGKLKEKESFGEISVLLQVPFTCTIITKKEVEMAIIEDKDLFVA
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Molecular Weight
48 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CNBD1, or cyclic nucleotide-binding domain 1, is a crucial protein involved in various cellular signaling pathways, particularly those mediated by cyclic nucleotides such as cAMP and cGMP. Its role in regulating processes such as neurotransmission and muscle contraction has garnered significant interest within the fields of molecular biology and biochemistry. The study of CNBD1 recombinant protein is particularly important for understanding its function in intracellular signaling cascades. By expressing and purifying CNBD1 as a recombinant protein, researchers can investigate its structural properties, binding affinities, and interaction with ligands. Additionally, recombinant CNBD1 provides a valuable tool for exploring potential therapeutic targets for disorders linked to dysregulated cyclic nucleotide signaling, including heart disease, neurodegenerative disorders, and metabolic syndromes. The advancements in recombinant DNA technology have enabled scientists to produce CNBD1 in various expression systems, facilitating detailed biochemical analyses and functional assays. As the understanding of cyclic nucleotide signaling continues to evolve, the study of CNBD1 and its recombinant forms remains a focal point, driving forward the development of novel therapeutic strategies and enhancing our comprehension of cellular communication mechanisms.
