Analytical Data
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Gene name
ERFE
- Application
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Alternative Names
ERFE；C1QTNF15；CTRP15；FAM132B；Erythroferrone
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Species
Human
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Source
HEK293
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Tag
N-His tag
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q4G0M1
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Expression Region
195-354aa
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AA Sequence
PGPRAPRVEAAFLCRLRRDALVERRALHELGVYYLPDAEGAFRRGPGLNLTSGQYRAPVAGFYALAATLHVALGEPPRRGPPRPRDHLRLLICIQSRCQRNASLEAIMGLESSSELFTISVNGVLYLQMGQWTSVFLDNASGCSLTVRSGSHFSAVLLGV
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Molecular Weight
18kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Identification
Protein Description
ERFE (Exercise-Induced Myokine with Endocrine Function) is a protein that has garnered significant attention in recent research due to its potential role in regulating metabolism and energy homeostasis. Initially identified as a myokine released from skeletal muscle during physical exercise, ERFE has been shown to influence various physiological processes, including the modulation of liver function and the regulation of blood glucose levels. Studies suggest that ERFE may possess protective effects against metabolic disorders, such as obesity and type 2 diabetes, by enhancing insulin sensitivity and promoting the uptake of glucose and lipids in peripheral tissues. Additionally, its involvement in inflammation and stress responses further highlights its importance in metabolic health. The exploration of ERFE's mechanisms of action, signaling pathways, and interactions with other hormones and factors is ongoing, providing valuable insights that may inform therapeutic strategies for metabolic diseases. Understanding ERFE’s role in the intricate network of muscle-to-organ communication is crucial, particularly as researchers seek to uncover innovative approaches to enhance metabolic health through lifestyle interventions like exercise and diet. Overall, the study of ERFE as a recombinant protein opens up new avenues for experimental research and potential clinical applications, paving the way for novel treatments aimed at mitigating the impacts of metabolic syndromes and improving overall metabolic health.
