Analytical Data
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Gene name
SMOC1
- Application
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Alternative Names
SMOC1；SPARC-related modular calcium-binding Protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H4F8-2
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Expression Region
1-435aa
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AA Sequence
MLPARCARLL TPHLLLVLVQ LSPARGHRTT GPRFLISDRD PQCNLHCSRT QPKPICASDG RSYESMCEYQ RAKCRDPTLG VVHRGRCKDA GQSKCRLERA QALEQAKKPQ EAVFVPECGE DGSFTQVQCH TYTGYCWCVT PDGKPISGSS VQNKTPVCSG SVTDKPLSQG NSGRKDDGSK PTPTMETQPV FDGDEITAPT LWIKHLVIKD SKLNNTNIRN SEKVYSCDQE RQSALEEAQQ NPREGIVIPE CAPGGLYKPV QCHQSTGYCW CVLVDTGRPL PGTSTRYVMP SCESDARAKT TEADDPFKDR ELPGCPEGKK MEFITSLLDA LTTDMVQAIN SAAPTGGGRF SEPDPSHTLE ERVVHWYFSQ LDSNSSNDIN KREMKPFKRY VKKKAKPKKC ARRFTDYCDL NKDKVISLPE LKGCLGVSKE VGRLV
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Molecular Weight
47 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SMOC1, or SMAD (Mothers Against Decapentaplegic) and Osteogenesis Molecular Combinatory protein 1, is a multifunctional protein that plays a critical role in various biological processes, including embryonic development, cell differentiation, and tissue homeostasis. It is a member of the SMOC family, which is known for its involvement in modulating signaling pathways, particularly those related to transforming growth factor-beta (TGF-β) and bone morphogenetic proteins (BMPs). Recent studies have suggested that SMOC1 may have significant implications in pathological conditions such as fibrosis, cancer, and cardiovascular diseases, due to its regulatory role in extracellular matrix dynamics and cell proliferation. The interest in SMOC1 recombinant proteins has surged as researchers aim to elucidate its molecular mechanisms, explore its potential as a therapeutic target, and assess its application in regenerative medicine. Recombinant forms of SMOC1 can be utilized in various assays to dissect its functions and interactions within cellular systems, paving the way for innovative approaches in treating diseases influenced by dysregulated signaling pathways. As such, understanding the structure-function relationship of SMOC1 and its interactions with other biomolecules is paramount for harnessing its therapeutic potential and advancing our knowledge of tissue development and repair mechanisms.
