Analytical Data
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基因名
SMOC1
- Application
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别名
SMOC1；SPARC-related modular calcium-binding Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H4F8-2
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表达区间
1-435aa
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氨基酸序列
MLPARCARLL TPHLLLVLVQ LSPARGHRTT GPRFLISDRD PQCNLHCSRT QPKPICASDG RSYESMCEYQ RAKCRDPTLG VVHRGRCKDA GQSKCRLERA QALEQAKKPQ EAVFVPECGE DGSFTQVQCH TYTGYCWCVT PDGKPISGSS VQNKTPVCSG SVTDKPLSQG NSGRKDDGSK PTPTMETQPV FDGDEITAPT LWIKHLVIKD SKLNNTNIRN SEKVYSCDQE RQSALEEAQQ NPREGIVIPE CAPGGLYKPV QCHQSTGYCW CVLVDTGRPL PGTSTRYVMP SCESDARAKT TEADDPFKDR ELPGCPEGKK MEFITSLLDA LTTDMVQAIN SAAPTGGGRF SEPDPSHTLE ERVVHWYFSQ LDSNSSNDIN KREMKPFKRY VKKKAKPKKC ARRFTDYCDL NKDKVISLPE LKGCLGVSKE VGRLV
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分子量
47 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SMOC1, or SMAD (Mothers Against Decapentaplegic) and Osteogenesis Molecular Combinatory protein 1, is a multifunctional protein that plays a critical role in various biological processes, including embryonic development, cell differentiation, and tissue homeostasis. It is a member of the SMOC family, which is known for its involvement in modulating signaling pathways, particularly those related to transforming growth factor-beta (TGF-β) and bone morphogenetic proteins (BMPs). Recent studies have suggested that SMOC1 may have significant implications in pathological conditions such as fibrosis, cancer, and cardiovascular diseases, due to its regulatory role in extracellular matrix dynamics and cell proliferation. The interest in SMOC1 recombinant proteins has surged as researchers aim to elucidate its molecular mechanisms, explore its potential as a therapeutic target, and assess its application in regenerative medicine. Recombinant forms of SMOC1 can be utilized in various assays to dissect its functions and interactions within cellular systems, paving the way for innovative approaches in treating diseases influenced by dysregulated signaling pathways. As such, understanding the structure-function relationship of SMOC1 and its interactions with other biomolecules is paramount for harnessing its therapeutic potential and advancing our knowledge of tissue development and repair mechanisms.
