Cat: PAX2000-11179

Recombinant Human SEC11L1 Protein,GST

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Analytical Data

  • Gene name

    SEC11L1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    SEC11A; SEC11L1; SPC18; SPCS4A; Signal peptidase complex catalytic subunit SEC11A; Endopeptidase SP18; Microsomal signal peptidase 18 kDa subunit; SPase 18 kDa subunit; SEC11 homolog A; SEC11-like protein 1; SPC18

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P67812

  • Expression Region

    1-179 aa

  • AA Sequence

    MLSLDFLDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE

  • Molecular Weight

    47 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

SEC11L1, or SEC11 like 1, is a member of the Sec11 family of proteins that play a crucial role in the biosynthesis and maturation of secretory proteins. Research has highlighted its importance in cellular processes such as protein translocation and processing within the endoplasmic reticulum (ER). Disruptions in SEC11L1 function have been linked to various pathological conditions, including immune disorders and cancer. Its potential role in influencing cellular responses to stress and its involvement in the Golgi apparatus function make SEC11L1 a promising target for therapeutic interventions. Furthermore, studies have shown that SEC11L1 may interact with other key proteins and pathways, thereby influencing intracellular signaling and metabolic processes. As a result, understanding the structure, function, and regulatory mechanisms of SEC11L1 is essential for elucidating its biological significance and potential applications in biotechnology and medicine. Research efforts aim to explore SEC11L1’s role in specific diseases, its potential as a biomarker, and its application in targeted therapies, making it a significant focus within the fields of molecular biology and pharmacology.

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