Analytical Data
-
基因名
SEC11L1
- Application
-
别名
SEC11A; SEC11L1; SPC18; SPCS4A; Signal peptidase complex catalytic subunit SEC11A; Endopeptidase SP18; Microsomal signal peptidase 18 kDa subunit; SPase 18 kDa subunit; SEC11 homolog A; SEC11-like protein 1; SPC18
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P67812
-
表达区间
1-179 aa
-
氨基酸序列
MLSLDFLDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE
-
分子量
47 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Recombinant Human PAPPA2 Protein，His
Cat：PA1000-6991
Recombinant Human SDSL Protein，His
Cat：PAX2000-11178
Protein Description
SEC11L1, or SEC11 like 1, is a member of the Sec11 family of proteins that play a crucial role in the biosynthesis and maturation of secretory proteins. Research has highlighted its importance in cellular processes such as protein translocation and processing within the endoplasmic reticulum (ER). Disruptions in SEC11L1 function have been linked to various pathological conditions, including immune disorders and cancer. Its potential role in influencing cellular responses to stress and its involvement in the Golgi apparatus function make SEC11L1 a promising target for therapeutic interventions. Furthermore, studies have shown that SEC11L1 may interact with other key proteins and pathways, thereby influencing intracellular signaling and metabolic processes. As a result, understanding the structure, function, and regulatory mechanisms of SEC11L1 is essential for elucidating its biological significance and potential applications in biotechnology and medicine. Research efforts aim to explore SEC11L1’s role in specific diseases, its potential as a biomarker, and its application in targeted therapies, making it a significant focus within the fields of molecular biology and pharmacology.
