Analytical Data
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Gene name
ABHD18
- Application
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Alternative Names
ABHD18；C4orf29；Protein ABHD18
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q0P651
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Expression Region
25-414aa
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AA Sequence
RPEDLK RLFEFRKMIG NRERCQNLVS SDYPVHIDKI EEQSDCKILD GHFVSPMAHY VPDIMPIESV IARFQFIVPK EWNSKYRPVC IHLAGTGDHH YWRRRTLMAR PMIKEARMAS LLLENPYYGC RKPKDQVRSS LKNVSDLFVM GGALVLESAA LLHWLEREGY GPLGMTGISM GGHMASLAVS NWPKPMPLIP CLSWSTASGV FTTTDSFKMG QEFVKHFTSS ADKLTNLNLV SRTLNLDISN QVVSQKPADC HNSSKTSVSA TSEGLLLQDT SKMKRFNQTL STNKSGYTSR NPQSYHLLSK EQSRNSLRKE SLIFMKGVMD ECTHVANFSV PVDPSLIIVV QAKEDAYIPR TGVRSLQEIW PGCEIRYLEG GHISAYLFKQ GLFR
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Molecular Weight
46.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ABHD18, a member of the α/β hydrolase family, has gained attention in recent years due to its potential roles in lipid metabolism and regulation of cellular processes. This enzyme is implicated in the hydrolysis of bioactive lipid species, which play critical roles in various physiological functions, including inflammation, cell signaling, and membrane dynamics. Research has suggested that ABHD18 may influence the levels of certain lipids, impacting metabolic pathways and possibly contributing to the development of metabolic disorders. Additionally, emerging studies highlight its potential as a therapeutic target for diseases linked to lipid dysregulation, such as obesity, diabetes, and neurodegenerative conditions. The recombinant expression of ABHD18 allows for the detailed study of its enzymatic properties, interaction with substrates, and functional mechanisms within cellular contexts. Furthermore, the protein’s crystal structure determination could provide insights into its catalytic mechanism and facilitate the design of specific inhibitors or modulators. Understanding the biochemical pathways involving ABHD18 could unveil novel strategies for the treatment of lipid-related diseases and uncover its broader significance in human health. Overall, the study of ABHD18 as a recombinant protein holds promise for elucidating its biological functions and therapeutic potential, paving the way for advancements in biomedical research focused on lipid metabolism and associated disorders.
