Analytical Data
-
Gene name
CGGBP1
- Application
-
Alternative Names
20 kDa CGG binding Protein; 20 kDa CGG-binding Protein; CGBP1_HUMAN; CGG binding Protein 1; CGG triplet repeat binding Protein 1; CGG triplet repeat-binding Protein 1
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9UFW8
-
Expression Region
1-167aa
-
AA Sequence
MERFVVTAPP ARNRSKTALY VTPLDRVTEF GGELHEDGGK LFCTSCNVVL NHVRKSAISD HLKSKTHTKR KAEFEEQNVR KKQRPLTASL QCNSTAQTEK VSVIQDFVKM CLEANIPLEK ADHPAVRAFL SRHVKNGGSI PKSDQLRRAY LPDGYENENQ LLNSQDC
-
Molecular Weight
45.2 KDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CGGBP1 (C1Q gene family member) is a nuclear protein that plays a significant role in various cellular processes, including DNA damage response, cell proliferation, and immune regulation. Initially identified as a transcriptional regulator, CGGBP1 has garnered attention for its involvement in tumor biology, as its expression levels are often altered in various cancers. Moreover, CGGBP1 has been linked to the modulation of epigenetic mechanisms, influencing gene expression patterns and potentially impacting tumorigenesis. Recent studies have shown that CGGBP1 may interact with chromatin-modifying complexes and participate in the repair of DNA damage, highlighting its importance in maintaining genomic stability. As a result, the recombinant expression of CGGBP1 protein has become a focal point for researchers aiming to elucidate its functional complexities and therapeutic potential. Developing recombinant CGGBP1 not only facilitates detailed characterization of its biochemical properties and interactions but also offers a platform for exploring its role in cancer biology and other diseases. Understanding the molecular mechanisms of CGGBP1 could pave the way for new strategies in cancer treatment and provide insights into the broader implications of nuclear proteins in cellular homeostasis and disease development. This makes CGGBP1 a compelling target for both basic research and therapeutic applications, as scientists aim to leverage its functional characteristics for innovative approaches in medical science.
