Analytical Data
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Gene name
CDYL
- Application
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Alternative Names
CDY-like; CDY-like autosomal; Cdyl; CDYL: chromodomain Protein Y-like; CDYL1; CDYL1_HUMAN; chromodomain Protein Y chromosome-like 6; Chromodomain Protein Y like; Chromodomain Y-like Protein; DKFZP586C1622; MGC131936
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y232
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Expression Region
1-598
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AA Sequence
MTFQASHRSA WGKSRKKNWQ YEGPTQKLFL KRNNVSAPDG PSDPSISVSS EQSGAQQPPA LQVERIVDKR KNKKGKTEYL VRWKGYDSED DTWEPEQHLV NCEEYIHDFN RRHTEKQKES TLTRTNRTSP NNARKQISRS TNSNFSKTSP KALVIGKDHE SKNSQLFAAS QKFRKNTAPS LSSRKNMDLA KSGIKILVPK SPVKSRTAVD GFQSESPEKL DPVEQGQEDT VAPEVAAEKP VGALLGPGAE RARMGSRPRI HPLVPQVPGP VTAAMATGLA VNGKGTSPFM DALTANGTTN IQTSVTGVTA SKRKFIDDRR DQPFDKRLRF SVRQTESAYR YRDIVVRKQD GFTHILLSTK SSENNSLNPE VMREVQSALS TAAADDSKLV LLSAVGSVFC CGLDFIYFIR RLTDDRKRES TKMAEAIRNF VNTFIQFKKP IIVAVNGPAI GLGASILPLC DVVWANEKAW FQTPYTTFGQ SPDGCSTVMF PKIMGGASAN EMLLSGRKLT AQEACGKGLV SQVFWPGTFT QEVMVRIKEL ASCNPVVLEE SKALVRCNMK MELEQANERE CEVLKKIWGS AQGMDSMLKY LQRKIDEF
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Molecular Weight
66.4 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CDYL (Cancer/Developmental Protein with a C2H2 Zinc Finger) is a protein implicated in various biological processes, including gene regulation and chromatin remodeling. Its involvement in cancer development and progression has garnered significant research interest, as aberrations in CDYL expression and function have been associated with several types of tumors. The protein acts as a critical epigenetic regulator, influencing the expression of genes that control cell growth, differentiation, and apoptosis. As a repressor of transcription, CDYL interacts with chromatin-modifying complexes, thereby participating in the regulation of gene expression networks essential for normal cellular functions and development. Due to its dual roles in both oncogenic and developmental pathways, understanding the structure and function of CDYL is crucial for elucidating its potential as a therapeutic target in cancer. Recent advances in protein expression and purification techniques have facilitated the production of recombinant CDYL, allowing researchers to conduct in-depth studies on its molecular mechanisms, interactions with DNA and other proteins, and its role in malignancies. Investigating recombinant CDYL provides insights that could lead to novel strategies for cancer treatment by modulating its activity or mimicking its function, offering a promising avenue for future therapeutic interventions.
