Cat: PA2000-6629

Recombinant Human CDYL2 Protein,GST

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Analytical Data

  • Gene name

    CDYL2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    CDYL2; Chromodomain Y-like Protein 2; CDY-like 2

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8N8U2

  • Expression Region

    1-506aa

  • AA Sequence

    MASGDLYEVE RIVDKRKNKK GKWEYLIRWK GYGSTEDTWE PEHHLLHCEE FIDEFNGLHM SKDKRIKSGK QSSTSKLLRD SRGPSVEKLS HRPSDPGKSK GTSHKRKRIN PPLAKPKKGY SGKPSSGGDR ATKTVSYRTT PSGLQIMPLK KSQNGMENGD AGSEKDERHF GNGSHQPGLD LNDHVGEQDM GECDVNHATL AENGLGSALT NGGLNLHSPV KRKLEAEKDY VFDKRLRYSV RQNESNCRFR DIVVRKEEGF THILLSSQTS DNNALTPEIM KEVRRALCNA ATDDSKLLLL SAVGSVFCSG LDYSYLIGRL SSDRRKESTR IAEAIRDFVK AFIQFKKPIV VAINGPALGL GASILPLCDI VWASEKAWFQ TPYATIRLTP AGCSSYTFPQ ILGVALANEM LFCGRKLTAQ EACSRGLVSQ VFWPTTFSQE VMLRVKEMAS CSAVVLEESK CLVRSFLKSV LEDVNEKECL MLKQLWSSSK GLDSLFSYLQ DKIYEV

  • Molecular Weight

    82.9 KDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

CDYL2, or Chromodomain Y-like 2, is a protein that has garnered significant interest in recent years due to its potential roles in epigenetic regulation and disease pathology. It is a member of the CDYL family, which is known for its involvement in chromatin remodeling and transcriptional regulation. Research has indicated that CDYL2 may play a crucial role in various biological processes, including cellular proliferation, differentiation, and apoptosis. Dysregulation of CDYL2 has been associated with several diseases, including cancer and neurological disorders, suggesting its importance as a therapeutic target. Studies have shown that CDYL2 interacts with different proteins and chromatin components, influencing gene expression patterns. This makes the understanding of CDYL2's structure, function, and interactions essential for elucidating its role in health and disease. Given the complexity of its regulatory mechanisms, the exploration of CDYL2 as a recombinant protein offers valuable insights into its biological functions and potential applications in targeted therapies. Furthermore, developing CDYL2-based assays could aid in drug discovery and the identification of novel biomarkers for disease. Overall, CDYL2 is an intriguing subject for research, highlighting the interplay between chromatin dynamics and cellular processes, with wider implications for understanding and treating various diseases.

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