Analytical Data
-
Gene name
CDY2
- Application
-
Alternative Names
CDY2A; CDY2;; CDY2B; Testis-specific chromodomain Protein Y 2; EC 2.3.1.48
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9Y6F7
-
Expression Region
1-541
-
AA Sequence
MASQEFEVEA IVDKRQDKNG NTQYLVRWKG YDKQDDTWEP EQHLMNCEKC VHDFNRRQTE KQKKLTWTTT SRIFSNNARR RTSRSTKANY SKNSPKTPVT DKHHRSKNCK LFAASKNVRR KAASTLSDTK NMEIINSTIE TLAPDSPFDH KKTVSGFQKL EKLDPIAADQ QDTVVFKVTE GKLLRDPLSH PGAEQTGIQN KTQMHPLMSQ MSGSVTASMA TGSATRKGIV VLIDPLAANG TTDMHTSVPR VKGGQRNITD DSRGQPFIKK MHFTIRLTES AITYRDIVVK KEDGFTQIVL STRSTEKNAL NTEVIKEMVN ALNSAAADDS KLVLFSAAGS VFCCGLDFGY FVRHLRNDRN TASLEMVDTI KNFVNTFIQF KKPIVVSVNG PAIGLGASIL PLCDLVWANE KAWFQTPYTT FGQSPDGCSS ITFPKMMGKA SANEMLIAGR KLTAREACAK GLVSQVFLTG TFTQEVMIQI KELASYNAIV LEECKALVRC NIKLELEQAN ERECEVLRKI WSSAQGIESM LKYVENKIDE F
-
Molecular Weight
60.5 KDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CDY2 (Chromodomain Y-like 2) is a protein that plays a crucial role in male fertility and spermatogenesis. It is primarily expressed in the male germ cells and is implicated in the regulation of gene expression through its chromodomain, which allows it to interact with methylated histones, thereby influencing chromatin structure and function. Research on CDY2 has gained significance due to its potential involvement in various reproductive disorders and infertility issues. Recent studies have shown that mutations or altered expression levels of CDY2 can lead to impaired sperm development and functionality, which highlights its importance in understanding male reproductive health. Moreover, the generation of recombinant CDY2 proteins has opened new avenues for investigating the molecular mechanisms underlying its functions. By producing these proteins in vitro, researchers can conduct detailed analyses of CDY2's interactions with other nuclear proteins and explore its role in epigenetic regulation during spermatogenesis. As the field progresses, the study of CDY2 not only contributes to a deeper comprehension of male infertility but also presents opportunities for potential therapeutic approaches aimed at restoring fertility. Thus, exploring the properties and mechanisms of CDY2 recombinant proteins is a vital step towards elucidating their biological relevance and potential clinical applications in reproductive health.
