Analytical Data
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Gene name
RTDR1
- Application
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Alternative Names
4933431K05Rik; MCG5994. isoform CRA_b; MGC16968; Rhabdoid tumor deletion region gene 1; Rhabdoid tumor deletion region protein 1; RTDR1; RTDR1_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UHP6
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Expression Region
1-348 aa
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AA Sequence
MAHSQNSLEL PININATQIT TAYGHRALPK LKEELQSEDL QTRQKALMAL CDLMHDPECI YKAMNIGCME NLKALLKDSN SMVRIKTTEV LHITASHSVG RYAFLEHDIV LALSFLLNDP SPVCRGNLYK AYMQLVQVPR GAQEIISKGL ISSLVWKLQV EVEEEEFQEF ILDTLVLCLQ EDATEALGSN VVLVLKQKLL SANQNIRSKA ARALLNVSIS REGKKQVCHF DVIPILVHLL KDPVEHVKSN AAGALMFATV ITEGKYAALE AQAIGLLLEL LHSPMTIARL NATKALTMLA EAPEGRKALQ THVPTFRAME VETYEKPQVA EALQRAARIA ISVIEFKP
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Molecular Weight
38.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RTDR1 (Regulated translational death regulator 1) is a recently identified protein that plays a critical role in cellular responses to stress and apoptosis. Research into RTDR1 began as scientists sought to understand the mechanisms of cellular regulation and death, particularly in the context of cancer and neurodegenerative diseases. Expression of RTDR1 has been found to be tightly regulated, indicating its potential as an important factor in the control of cell survival under harsh conditions. Initial studies revealed that RTDR1 interacts with various signaling pathways and proteins involved in the regulation of apoptosis, influencing the balance between cell survival and death. Given its role in modulating stress responses and its potential implications in disease progression, RTDR1 has attracted increasing attention as a therapeutic target. Researchers are exploring its biochemical properties, expression patterns in different tissues, and potential as a biomarker for disease states. Understanding RTDR1's function and mechanisms of action may provide new insights into the development of treatment strategies for conditions where regulation of cell death is disrupted, such as in tumors or neurodegeneration. Thus, continued investigation into RTDR1 could uncover novel pathways for therapeutic intervention and contribute to the broader field of apoptosis research.
