Analytical Data
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基因名
HSPD1 / HSP60
- Application
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别名
HSPD1 / HSP60；
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P10809
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表达区间
27-573aa
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氨基酸序列
AKDV KFGADARALM LQGVDLLADA VAVTMGPKGR TVIIEQSWGS PKVTKDGVTV AKSIDLKDKY KNIGAKLVQD VANNTNEEAG DGTTTATVLA RSIAKEGFEK ISKGANPVEI RRGVMLAVDA VIAELKKQSK PVTTPEEIAQ VATISANGDK EIGNIISDAM KKVGRKGVIT VKDGKTLNDE LEIIEGMKFD RGYISPYFIN TSKGQKCEFQ DAYVLLSEKK ISSIQSIVPA LEIANAHRKP LVIIAEDVDG EALSTLVLNR LKVGLQVVAV KAPGFGDNRK NQLKDMAIAT GGAVFGEEGL TLNLEDVQPH DLGKVGEVIV TKDDAMLLKG KGDKAQIEKR IQEIIEQLDV TTSEYEKEKL NERLAKLSDG VAVLKVGGTS DVEVNEKKDR VTDALNATRA AVEEGIVLGG GCALLRCIPA LDSLTPANED QKIGIEIIKR TLKIPAMTIA KNAGVEGSLI VEKIMQSSSE VGYDAMAGDF VNMVEKGIID PTKVVRTALL DAAGVASLLT TAEVVVTEIP KEEKDPGMGA MGGMGGGMGG GMF
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HSPD1, also known as Heat Shock Protein 60 (HSP60), is a highly conserved mitochondrial chaperonin that plays a crucial role in protein folding and assembly within the mitochondria. It facilitates the proper folding of newly synthesized proteins, thereby maintaining mitochondrial function and cellular homeostasis. Dysregulation or mutations in HSPD1 have been linked to various diseases, including neurodegenerative disorders and certain types of cancer. The study of recombinant HSPD1, or HSP60, has garnered attention as researchers seek to better understand its functional mechanisms and interactions with other cellular components. Recombinant protein technology allows for the production of HSP60 in vitro, enabling researchers to investigate its structure, dynamics, and role in diseases more effectively. Additionally, recombinant HSPD1 has potential therapeutic applications, including the development of vaccines and targeted therapies that harness the immune response against cancer cells or aberrant proteins. The exploration of HSPD1/HSP60 as a biomarker for disease progression and prognosis is also an emerging field, shedding light on its potential role in diagnostic and therapeutic strategies. Thus, the study of HSPD1/HSP60 recombinant protein not only contributes to our understanding of mitochondrial biology but also holds promise for the advancement of medical research and therapeutic interventions.
