Analytical Data
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基因名
RPUSD2
- Application
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别名
C15orf19; C18B11; C18B11 homolog; FLJ31409; RNA pseudouridylate synthase domain containing 2; RNA pseudouridylate synthase domain containing protein 2; RNA pseudouridylate synthase domain-containing protein 2; RPUSD 2; RPUSD2; RUSD2_HUMAN
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IZ73
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表达区间
1-545 aa
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氨基酸序列
MWLDRRGWLR VLGHWRYDLR RPSFTRTWSG DKGPMAETVS TQVGTEGGLR ASHQQNGDAG GDAKVELSPG PPKPAGREVE PAPVGGEHPS AAAPGPGKHK KRRGATRERV VPPPKKRRTG VSFGDEHFAE TSYYFEGGLR KVRPYYFDFR TYCKGRWVGH SLLHVFSTEF RAQPLAYYEA AVRAGRLQLN EKPVQDLNIV LKDNDFLRNT VHRHEPPVTA EPIRLLAENE DVVVVDKPSS IPVHPCGRFR HNTVIFILGK EHQLKELHPL HRLDRLTSGV LMFAKTAAVS ERIHEQVRDR QLEKEYVCRV EGEFPTEEVT CKEPILVVSY KVGVCRVDPR GKPCETVFQR LSYNGQSSVV RCRPLTGRTH QIRVHLQFLG HPILNDPIYN SVAWGPSRGR GGYIPKTNEE LLRDLVAEHQ AKQSLDVLDL CEGDLSPGLT DSTAPSSELG KDDLEELAAA AQKMEEVAEA APQELDTIAL ASEKAVETDV MNQETDPLCA ECRLVRQDPL PQDLVMFLHA LRYKGPGFEY FSPMPAWAQD DWQKD
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分子量
61.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The RPUSD2 protein, known as RNA pseudouridylate synthase 2, is a member of the RPUSD family and is primarily involved in the modification of RNA molecules through the pseudouridylation process. This modification, which occurs at specific sites within RNA, plays a critical role in RNA stability, translation efficiency, and overall cellular function. Research has shown that RPUSD2 is particularly important in the development and functioning of various tissues, including the nervous system and immune response. Given its potential implications in diseases, including cancer and neurodegenerative disorders, understanding the structural and functional aspects of RPUSD2 is paramount. Recent studies have focused on elucidating the enzymatic mechanisms, substrate specificity, and the interactions of RPUSD2 with other cellular components. This research aims to uncover the biological significance of RPUSD2 and its potential as a therapeutic target, highlighting the need for detailed investigations into its role in RNA metabolism and cellular homeostasis. As research progresses, the insights gained from RPUSD2 studies could pave the way for novel strategies in disease treatment and the development of RNA-based therapies.
