Analytical Data
-
基因名
SPINT1
- Application
-
别名
SPINT1；HAI1；Kunitz-type protease inhibitor 1
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O43278
-
表达区间
36-529aa
-
氨基酸序列
GPPPA PPGLPAGADC LNSFTAGVPG FVLDTNASVS NGATFLESPT VRRGWDCVRA CCTTQNCNLA LVELQPDRGE DAIAACFLIN CLYEQNFVCK FAPREGFINY LTREVYRSYR QLRTQGFGGS GIPKAWAGID LKVQPQEPLV LKDVENTDWR LLRGDTDVRV ERKDPNQVEL WGLKEGTYLF QLTVTSSDHP EDTANVTVTV LSTKQTEDYC LASNKVGRCR GSFPRWYYDP TEQICKSFVY GGCLGNKNNY LREEECILAC RGVQGGPLRG SSGAQATFPQ GPSMERRHPV CSGTCQPTQF RCSNGCCIDS FLECDDTPNC PDASDEAACE KYTSGFDELQ RIHFPSDKGH CVDLPDTGLC KESIPRWYYN PFSEHCARFT YGGCYGNKNN FEEEQQCLES CRGISKKDVF GLRREIPIPS TGSVEMAVAV FLVICIVVVV AILGYCFFKN QRKDFHGHHH HPPPTPASST VSTTEDTEHL VYNHTTRPL
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SPINT1, or Serine Peptidase Inhibitor, Kunitz Type 1, is a crucial protein that functions as a serine protease inhibitor. It plays a significant role in regulating various physiological processes, including blood pressure, inflammation, and tissue remodeling. Research surrounding SPINT1 has gained interest due to its association with several human diseases, particularly its potential implications in cancer progression and metastasis. Alterations in SPINT1 expression levels have been linked to poor prognosis in various malignancies, emphasizing the need for a deeper understanding of its functional mechanisms. Recent studies suggest that SPINT1 may modulate the tumor microenvironment and influence interactions between cancer cells and surrounding stromal components. Moreover, SPINT1 has been identified as a potential biomarker for certain types of cancer, highlighting its potential utility in diagnostic and therapeutic strategies. Investigating SPINT1 recombinant proteins can facilitate the elucidation of its biological functions and interactions, offering insights into therapeutic targets for cancer treatment and other related conditions. As researchers explore the pathways involving SPINT1, there is a growing interest in developing SPINT1-based interventions, which could lead to novel strategies for managing diseases characterized by dysregulated proteolytic activity. Overall, the study of SPINT1 recombinant proteins stands at the intersection of fundamental biology and clinical application, making it a promising area for future research.
