Analytical Data
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Gene name
RPS8
- Application
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Alternative Names
40S ribosomal protein S8; OK/SW-cl.83; OTTHUMP00000010160; OTTHUMP00000010161; Ribosomal protein S8; RPS8; RS8_HUMAN; S8
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P62241
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Expression Region
2-208 aa
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AA Sequence
GISRDNWHK RRKTGGKRKP YHKKRKYELG RPAANTKIGP RRIHTVRVRG GNKKYRALRL DVGNFSWGSE CCTRKTRIID VVYNASNNEL VRTKTLVKNC IVLIDSTPYR QWYESHYALP LGRKKGAKLT PEEEEILNKK RSKKIQKKYD ERKKNAKISS LLEEQFQQGK LLACIASRPG QCGRADGYVL EGKELEFYLR KIKARKGK
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Molecular Weight
24.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RPS8, or ribosomal protein S8, is a crucial component of the ribosome, a cellular machinery that facilitates protein synthesis. As part of the 40S ribosomal subunit in eukaryotes, RPS8 plays a significant role in translating mRNA into proteins, which are essential for various biological functions. Recent research has highlighted the importance of RPS8 in cellular processes beyond protein synthesis, such as its involvement in stress responses and cell growth regulation. Abnormalities in RPS8 expression have been linked to various diseases, including cancer, suggesting its potential as a biomarker for disease progression and a target for therapeutic intervention. The study of recombinant RPS8 proteins has gained traction due to their applications in structural biology and potential therapeutic uses. By producing and characterizing recombinant RPS8, researchers can gain insights into its functional mechanisms and how mutations may disrupt ribosomal activity, thereby understanding its role in diseases more deeply. Additionally, examining RPS8 interactions with other ribosomal proteins and RNA elements can shed light on the assembly and functionality of the ribosome as a whole. This growing body of work underscores the need for continued investigation into RPS8 and its broader implications in health and disease.
